基本信息:
- 专利标题： 간암에 대한 신규 바이오마커 및 그의 용도
- 专利标题（英）：NOVEL BIOMARKER FOR LIVER CANCER AND APPLICATIONS FOR SAME
- 申请号：PCT/KR2009/007202 申请日：2009-12-03
- 公开(公告)号：WO2010067984A3 公开(公告)日：2010-06-17
- 发明人： 송은영 , 이희구 , 염영일 , 지나영 , 이정일 , 강민아 , 김영주 , 강윤희 , 김재화
- 申请人： 한국생명공학연구원 , 송은영 , 이희구 , 염영일 , 지나영 , 이정일 , 강민아 , 김영주 , 강윤희 , 김재화
- 申请人地址： 대전광역시 유성구 어은동 52번지, 305-806 Daejeon KR
- 专利权人： 한국생명공학연구원,송은영,이희구,염영일,지나영,이정일,강민아,김영주,강윤희,김재화
- 当前专利权人： 한국생명공학연구원,송은영,이희구,염영일,지나영,이정일,강민아,김영주,강윤희,김재화
- 当前专利权人地址： 대전광역시 유성구 어은동 52번지, 305-806 Daejeon KR
- 代理机构： 양부현
- 优先权： KR10-2008-0125045 20081210; KR10-2009-0075199 20090814; KR10-2009-0075319 20090814
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; G01N33/574 ; C12N15/12
The present invention relates to the elucidation of a gene that can act as a novel marker for liver cancer diagnosis and to diagnostic and prognostic measurements of liver cancer using the same. More specifically, it relates to a diagnosis kit that enables diagnostic and prognostic measurement of a liver cancer using a preparation that measures expression levels of at least one gene selected from a group of liver cancer diagnosis markers consisting of S100P, NK4, CCL20, CSPG2, PLAU, MMP12, ESM-1, ABHD7, HCAPG, CXCL-3, Col5A2, MAGEA, GSN, CDC2, CST1, MELK, ATAD2, FAP and MSN and/or a method for diagnostic and prognostic measurement of liver cancer using the same. These have been discovered using normal liver tissues and liver cancer tissues collected from the same liver cancer patient of the present invention and represent the markers whose accuracy and reliability have been greatly improved as markers of liver cancer. The markers of the present invention can be used for the accurate diagnosis and prognosis of liver cancer.