发明申请
WO2010002115A3 FXA INHIBITORS WITH CYCLIC AMIDOXIME OR CYCLIC AMIDRAZONE AS P4 SUBUNIT, PROCESSES FOR THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS AND DERIVATIVES THEREOF
审中-公开
基本信息:
- 专利标题： FXA INHIBITORS WITH CYCLIC AMIDOXIME OR CYCLIC AMIDRAZONE AS P4 SUBUNIT, PROCESSES FOR THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS AND DERIVATIVES THEREOF
- 专利标题（中）：具有环状氨基嘧啶或环状阿司达唑钠P4亚基的FXA抑制剂及其制备方法和药物组合物及其衍生物
- 申请号：PCT/KR2009003008 申请日：2009-06-05
- 公开(公告)号：WO2010002115A3 公开(公告)日：2010-03-11
- 发明人： SONG HO YOUNG , CHO YOUNG LAG , LEE DAE YON , PARK HEE SOCK , BAEK SUNG YOON , CHAE SANG EUN , JO SANG HUI , KIM YEON OK , LEE HYANG SOOK , PARK JU HYUN , PARK TAE KYO , WOO SUNG HO , KIM YONG ZU
- 申请人： LEGOCHEM BIOSCIENCE LTD , SONG HO YOUNG , CHO YOUNG LAG , LEE DAE YON , PARK HEE SOCK , BAEK SUNG YOON , CHAE SANG EUN , JO SANG HUI , KIM YEON OK , LEE HYANG SOOK , PARK JU HYUN , PARK TAE KYO , WOO SUNG HO , KIM YONG ZU
- 专利权人： LEGOCHEM BIOSCIENCE LTD,SONG HO YOUNG,CHO YOUNG LAG,LEE DAE YON,PARK HEE SOCK,BAEK SUNG YOON,CHAE SANG EUN,JO SANG HUI,KIM YEON OK,LEE HYANG SOOK,PARK JU HYUN,PARK TAE KYO,WOO SUNG HO,KIM YONG ZU
- 当前专利权人： LEGOCHEM BIOSCIENCE LTD,SONG HO YOUNG,CHO YOUNG LAG,LEE DAE YON,PARK HEE SOCK,BAEK SUNG YOON,CHAE SANG EUN,JO SANG HUI,KIM YEON OK,LEE HYANG SOOK,PARK JU HYUN,PARK TAE KYO,WOO SUNG HO,KIM YONG ZU
- 优先权： KR20080064178 2008-07-03
- 主分类号： C07D413/12
- IPC分类号： C07D413/12
摘要：
The present invention relates to novel oxazolidinone derivatives with cyclic amidoxime or cyclic amidrazone group, pharmaceutically acceptable salts thereof, methods for preparing the same and pharmaceutical compositions comprising the same. The oxazolidinone derivatives with cyclic amidoxime or cyclic amidrazone group or the pharmaceutically acceptable salts thereof can be effectively used for the treatment of thromboembolism and tumor as an anticoagulant based on the inhibition of factor Xa.
摘要（中）：
本发明涉及具有环状偕胺肟或环状氨基腙基团的新型恶唑烷酮衍生物，其药学上可接受的盐，其制备方法以及包含其的药物组合物。 具有环状偕胺肟或环状氨基腙基的恶唑烷酮衍生物或其药学上可接受的盐基于抑制因子Xa可有效用于治疗血栓栓塞症和肿瘤作为抗凝剂。
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D413/00 | 杂环化合物，含两个或更多个杂环，至少有1个环有氮原子和氧原子作为仅有的杂环原子 |
| --------C07D413/02 | .含两个杂环 |
| ----------C07D413/12 | ..被含有杂原子的链作为键链连接的 |