基本信息:
- 专利标题: PEPTIDE DERIVED FROM A PROTEIN OF THE AQUAPORIN FAMILY
- 专利标题(中):从AQUAPORIN家族蛋白衍生的肽
- 申请号:PCT/FR2008001758 申请日:2008-12-17
- 公开(公告)号:WO2009106715A3 公开(公告)日:2009-10-22
- 发明人: DAL FARRA CLAUDE , DOMLOGE NOUHA , BOTTO JEAN-MARIE
- 申请人: SOC EXTRACTION PRINCIPES ACTIF , DAL FARRA CLAUDE , DOMLOGE NOUHA , BOTTO JEAN-MARIE
- 专利权人: SOC EXTRACTION PRINCIPES ACTIF,DAL FARRA CLAUDE,DOMLOGE NOUHA,BOTTO JEAN-MARIE
- 当前专利权人: SOC EXTRACTION PRINCIPES ACTIF,DAL FARRA CLAUDE,DOMLOGE NOUHA,BOTTO JEAN-MARIE
- 优先权: FR0708976 2007-12-21
- 主分类号: C07K4/00
- IPC分类号: C07K4/00 ; A61K8/64 ; A61K38/05 ; A61K38/06 ; A61K38/07 ; A61P17/00 ; A61Q19/00 ; C07K5/06 ; C07K5/08 ; C07K5/10
摘要:
The present invention relates to a peptide of general formula (I): R1-(AA)n-X1-X2-X3-PrO-X4-X5-X7-(AA)P-R2, derived from a protein of the aquaporin family. The present invention also relates to a cosmetic, nutraceutical or pharmaceutical composition comprising a peptide of general formula (I), as active ingredient. The invention also relates to the use of this new active agent in a cosmetic or nutraceutical composition for improving the hydration and the barrier function of the epidermis and for stimulating skin regeneration. The invention also relates to the use of this new active agent, for the preparation of a pharmaceutical, and in particular dermatological, composition for treating pathogenic dryness of the skin or of the mucous membranes. The invention also relates to a cosmetic treatment method for preventing and/or combating dryness of the skin and of the mucous membranes, and the manifestations of skin ageing.
摘要(中):
本发明涉及通式(I)的肽:衍生自水通道蛋白家族的蛋白质的R1-(AA)n-X1-X2-X3-PrO-X4-X5-X7-(AA)P-R2 。 本发明还涉及包含通式(I)的肽作为活性成分的化妆品,营养药物或药物组合物。 本发明还涉及这种新的活性剂在化妆品或营养组合物中用于改善表皮水合和屏障功能以及刺激皮肤再生的用途。 本发明还涉及这种新的活性剂用于制备药物,特别是用于治疗皮肤或粘膜病原性干燥的皮肤病学组合物的用途。 本发明还涉及用于预防和/或抵抗皮肤和粘膜干燥的美容治疗方法以及皮肤老化的表现。