基本信息:
- 专利标题： IMIDAZOPYRAZINES AS PROTEIN KINASE INHIBITORS
- 申请号：PCT/US2009031972 申请日：2009-01-26
- 公开(公告)号：WO2009097233A1 公开(公告)日：2009-08-06
- 发明人： RAINKA MATTHEW PAUL , VOSS MATTHEW ERNST , PETERSON LISA HELEN , FLEMING MIKE , BELANGER DAVID B , CURRAN PATRICK J , KULKARNI BHEEMASHANKAR A , YU TAO , ZHANG YONGLIAN , XIAO YUSHI , KEREKES ANGELA D , TAGAT JAYARAM R , DOLL RONALD J , SIDDIQUI M ARSHAD
- 申请人： SCHERING CORP , ALBANY MOLECULAR RES INC , RAINKA MATTHEW PAUL , VOSS MATTHEW ERNST , PETERSON LISA HELEN , FLEMING MIKE , BELANGER DAVID B , CURRAN PATRICK J , KULKARNI BHEEMASHANKAR A , YU TAO , ZHANG YONGLIAN , XIAO YUSHI , KEREKES ANGELA D , TAGAT JAYARAM R , DOLL RONALD J , SIDDIQUI M ARSHAD
- 专利权人： SCHERING CORP,ALBANY MOLECULAR RES INC,RAINKA MATTHEW PAUL,VOSS MATTHEW ERNST,PETERSON LISA HELEN,FLEMING MIKE,BELANGER DAVID B,CURRAN PATRICK J,KULKARNI BHEEMASHANKAR A,YU TAO,ZHANG YONGLIAN,XIAO YUSHI,KEREKES ANGELA D,TAGAT JAYARAM R,DOLL RONALD J,SIDDIQUI M ARSHAD
- 当前专利权人： SCHERING CORP,ALBANY MOLECULAR RES INC,RAINKA MATTHEW PAUL,VOSS MATTHEW ERNST,PETERSON LISA HELEN,FLEMING MIKE,BELANGER DAVID B,CURRAN PATRICK J,KULKARNI BHEEMASHANKAR A,YU TAO,ZHANG YONGLIAN,XIAO YUSHI,KEREKES ANGELA D,TAGAT JAYARAM R,DOLL RONALD J,SIDDIQUI M ARSHAD
- 优先权： US2401008 2008-01-28
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/4985 ; A61P29/00 ; A61P35/00
摘要：
In its many embodiments, the present invention provides a novel class of imidazopyrazine compounds as inhibitors of protein and/or Aurora kinases, methods of preparing such compounds, pharmaceutical compositions including one or more such compounds, methods of preparing pharmaceutical formulations including one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the protein or Aurora kinases using such compounds or pharmaceutical compositions.
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D487/00 | 在稠环系中含有氮原子作为仅有的杂环原子的杂环化合物，不包含在C07D451/00至C07D477/00组中 |
| --------C07D487/02 | .在稠合系中含有两个杂环 |
| ----------C07D487/04 | ..邻位稠合系 |