基本信息:
- 专利标题: INHIBITORS OF JNK AND METHODS FOR IDENTIFYING INHIBITORS OF JNK
- 专利标题(中):JNK的抑制剂和鉴定JNK的抑制剂的方法
- 申请号:PCT/US2008056341 申请日:2008-03-08
- 公开(公告)号:WO2008118626A3 公开(公告)日:2009-05-07
- 发明人: PELLECCHIA MAURIZIO
- 申请人: BURNHAM INST MEDICAL RESEARCH , PELLECCHIA MAURIZIO
- 专利权人: BURNHAM INST MEDICAL RESEARCH,PELLECCHIA MAURIZIO
- 当前专利权人: BURNHAM INST MEDICAL RESEARCH,PELLECCHIA MAURIZIO
- 优先权: US90593307 2007-03-08; US273607 2007-11-08
- 主分类号: G01N33/53
- IPC分类号: G01N33/53
摘要:
The invention provides methods, e.g., screening methods, for identifying modulators of the JNK/JIP interaction. The invention also provides kits comprising reagents for performing the methods of the invention. Also provided are compounds identified as modulators of the JNK/JIP interaction using the disclosed methods, pharmaceutical compositions and therepeutic methods using same.
摘要(中):
本发明提供了用于鉴定JNK / JIP相互作用的调节剂的方法,例如筛选方法。 本发明还提供包含用于实施本发明方法的试剂的试剂盒。 还提供了使用所公开的方法,药物组合物和使用它们的方法鉴定为JNK / JIP相互作用的调节剂的化合物。