基本信息:
- 专利标题： MODULAR NANOPARTICLES FOR ADAPTABLE VACCINES
- 申请号：PCT/US2008/054086 申请日：2008-02-15
- 公开(公告)号：WO2008115641A9 公开(公告)日：2008-09-25
- 发明人： MELLMAN, Ira, S. , FAHMY, Tarek, M. , SALTZMAN, Mark, W , CAPLAN, Michael, J.
- 申请人： YALE UNIVERSITY , MELLMAN, Ira, S. , FAHMY, Tarek, M. , SALTZMAN, Mark, W , CAPLAN, Michael, J.
- 申请人地址： Two Whitney Avenue New Haven, CT 06511 US
- 专利权人： YALE UNIVERSITY,MELLMAN, Ira, S.,FAHMY, Tarek, M.,SALTZMAN, Mark, W,CAPLAN, Michael, J.
- 当前专利权人： YALE UNIVERSITY,MELLMAN, Ira, S.,FAHMY, Tarek, M.,SALTZMAN, Mark, W,CAPLAN, Michael, J.
- 当前专利权人地址： Two Whitney Avenue New Haven, CT 06511 US
- 代理机构： PABST, Patrea, L. et al.
- 优先权： US60/890,133 20070215; US61/000,016 20071023
- 主分类号： A61K39/00
- IPC分类号： A61K39/00
摘要：
Modular nanoparticle vaccine compositions and methods of making and using the same have been developed. Modular nanoparticle vaccine compositions comprise an antigen encapsulated in a polymeric particle and adaptor elements which modularly couple functional elements to the particle. The modular design of these vaccine compositions, which involves flexible addition and subtraction of antigen, adjuvant, immune potentiators, molecular recognition and transport mediation elements, as well as intracellular uptake mediators, allows for exquisite control over variables that are important in optimizing an effective vaccine delivery system.
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K39/00 | 含有抗原或抗体的医药配制品 |