发明申请
WO2008100344A8 FLUORESCENT METHODS AND MATERIALS FOR DIRECTED BIOMARKER SIGNAL AMPLIFICATION
审中-公开
基本信息:
- 专利标题： FLUORESCENT METHODS AND MATERIALS FOR DIRECTED BIOMARKER SIGNAL AMPLIFICATION
- 申请号：PCT/US2007/080734 申请日：2007-10-08
- 公开(公告)号：WO2008100344A8 公开(公告)日：2008-08-21
- 发明人： GAYLORD, Brent, S. , HONG, Janice, W. , FU, Tsu-ju , SUN, Cheng, Jun
- 申请人： SIRIGEN INC. , GAYLORD, Brent, S. , HONG, Janice, W. , FU, Tsu-ju , SUN, Cheng, Jun
- 申请人地址： 5385 Hollister Avenue Suite 105 Santa Barbara, CA 93111 US
- 专利权人： SIRIGEN INC.,GAYLORD, Brent, S.,HONG, Janice, W.,FU, Tsu-ju,SUN, Cheng, Jun
- 当前专利权人： SIRIGEN INC.,GAYLORD, Brent, S.,HONG, Janice, W.,FU, Tsu-ju,SUN, Cheng, Jun
- 当前专利权人地址： 5385 Hollister Avenue Suite 105 Santa Barbara, CA 93111 US
- 代理机构： BACSI, Steven, G. et al.
- 优先权： US60/825,615 20061006
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.