基本信息:
- 专利标题： AUTOMATABLE ARTIFICIAL IMMUNE SYSTEM (AIS)
- 专利标题（中）：自动人工免疫系统（AIS）
- 申请号：PCT/US2007083795 申请日：2007-11-06
- 公开(公告)号：WO2008073635A2 公开(公告)日：2008-06-19
- 发明人： WARREN WILLIAM L , PARKHILL ROBERT , NGUYEN MICHAEL N , SANCHEZ-SCHMITZ GUZMAN , FAHLENKAMP HEATHER , HIGBEE RUSSELL , DRAKE III DONALD , KACHURIN ANATOLY , MOE DAVID
- 申请人： VAXDESIGN CORP , WARREN WILLIAM L , PARKHILL ROBERT , NGUYEN MICHAEL N , SANCHEZ-SCHMITZ GUZMAN , FAHLENKAMP HEATHER , HIGBEE RUSSELL , DRAKE III DONALD , KACHURIN ANATOLY , MOE DAVID
- 专利权人： VAXDESIGN CORP,WARREN WILLIAM L,PARKHILL ROBERT,NGUYEN MICHAEL N,SANCHEZ-SCHMITZ GUZMAN,FAHLENKAMP HEATHER,HIGBEE RUSSELL,DRAKE III DONALD,KACHURIN ANATOLY,MOE DAVID
- 当前专利权人： VAXDESIGN CORP,WARREN WILLIAM L,PARKHILL ROBERT,NGUYEN MICHAEL N,SANCHEZ-SCHMITZ GUZMAN,FAHLENKAMP HEATHER,HIGBEE RUSSELL,DRAKE III DONALD,KACHURIN ANATOLY,MOE DAVID
- 优先权： US59417106 2006-11-08
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; C12Q1/00 ; G01N33/531
摘要：
The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the normal tissues that interact with vaccines in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interactions with the immune system.
摘要（中）：
本发明涉及构建整合人工免疫系统的方法，所述整合人工免疫系统包含适当的体外细胞和组织构建体或其等价物以模拟与哺乳动物中的疫苗相互作用的正常组织。 人造免疫系统可用于体外检测候选疫苗的功效，因此可用于加速疫苗开发和检测与免疫系统的药物和化学相互作用。
公开/授权文献:
- WO2008073635A9 AUTOMATABLE ARTIFICIAL IMMUNE SYSTEM (AIS) 公开/授权日：2008-10-23