发明申请
WO2007134304A1 METHODS AND COMPOSITIONS FOR CONTROLLED AND SUSTAINED PRODUCTION AND DELIVERY OF PEROXIDES
审中-公开
基本信息:
- 专利标题: METHODS AND COMPOSITIONS FOR CONTROLLED AND SUSTAINED PRODUCTION AND DELIVERY OF PEROXIDES
- 专利标题(中):用于控制和持续生产和递送过氧化物的方法和组合物
- 申请号:PCT/US2007/068910 申请日:2007-05-14
- 公开(公告)号:WO2007134304A1 公开(公告)日:2007-11-22
- 发明人: WARD, Kevin , HUVARD, Gary , CARPENTER, Everette , SANDHU, Gurbhagat , BARBEE, Robert , SPIESS, Bruce
- 申请人: VIRGINIA COMMONWEALTH UNIVERSITY , WARD, Kevin , HUVARD, Gary , CARPENTER, Everette , SANDHU, Gurbhagat , BARBEE, Robert , SPIESS, Bruce
- 申请人地址: 800 E. Leigh Street Suite 113 Richmond, VA 23219 US
- 专利权人: VIRGINIA COMMONWEALTH UNIVERSITY,WARD, Kevin,HUVARD, Gary,CARPENTER, Everette,SANDHU, Gurbhagat,BARBEE, Robert,SPIESS, Bruce
- 当前专利权人: VIRGINIA COMMONWEALTH UNIVERSITY,WARD, Kevin,HUVARD, Gary,CARPENTER, Everette,SANDHU, Gurbhagat,BARBEE, Robert,SPIESS, Bruce
- 当前专利权人地址: 800 E. Leigh Street Suite 113 Richmond, VA 23219 US
- 代理机构: WHITHAM, Michael, E. et al.
- 优先权: US60/800,041 20060515
- 主分类号: C01D1/32
- IPC分类号: C01D1/32 ; C01D3/16 ; C01D7/26
摘要:
Methods and compositions for the controlled and sustained release of peroxides or oxygen to aqueous environments (e.g. a patient's body or circulatory system, or for other applications) or non-aqueous environments, include a material coating or encapsulating hydrogen peroxide, inorganic peroxides or peroxide adducts. In the case of peroxide adducts, and particularly in one type of embodiment, the peroxide adducts should be able to permeate the material, but water, hydrogen peroxide and inorganic peroxides should be able to permeate the material. The methods and compositions that allow the release of oxygen, H 2 O 2 or inorganic peroxides from peroxide adducts with movement of these moieties across a selectively permeable barrier into, preferably, an aqueous environment. In the case of hydrogen peroxide, it can be acted upon by catalase or other enzymes, or be simply degraded, or are otherwise acted upon by enzymes or catalysts embedded in the selectively permeable barrier to produce, for example, O 2 . Alternatively, hydrogen peroxide or inorganic peroxides can be delivered selectively to a site of action of cleaning, disinfecting or other applications.
摘要(中):
将过氧化物或氧气受控和持续释放到水性环境(例如患者的身体或循环系统或其他应用)或非水环境中的方法和组合物包括材料包衣或包封过氧化氢,无机过氧化物或过氧化物加合物 。 在过氧化物加合物的情况下,特别是在一种实施方案中,过氧化物加合物应能够渗透材料,但水,过氧化氢和无机过氧化物应能够渗透材料。 这些方法和组合物允许从过氧化物加合物释放氧,H 2 O 2 O 2或无机过氧化物,这些部分通过选择性渗透屏障移动,优选地为 水环境。 在过氧化氢的情况下,它可以被过氧化氢酶或其它酶作用,或被简单地降解,或者另外被嵌入选择性渗透屏障中的酶或催化剂作用,以产生例如O 2, / SUB>。 或者,过氧化氢或无机过氧化物可以选择性地递送到清洁,消毒或其它应用的作用部位。
IPC结构图谱:
C | 化学;冶金 |
--C01 | 无机化学 |
----C01D | 碱金属,即锂、钠、钾、铷、铯或钫的化合物 |
------C01D1/00 | 钠、钾或一般碱金属的氧化物或氢氧化物 |
--------C01D1/04 | .氢氧化物 |
----------C01D1/28 | ..纯化;分离 |
------------C01D1/32 | ...用吸附或沉淀法 |