基本信息:
- 专利标题： ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES
- 专利标题（中）：用于大型图书馆有效合成的酶编码方法
- 申请号：PCT/DK2006000685 申请日：2006-12-01
- 公开(公告)号：WO2007062664A2 公开(公告)日：2007-06-07
- 发明人： FRANCH THOMAS , LUNDORF MIKKEL DYBRO , JAKOBSEN SOEREN NYBOE , OLSEN EVA KAMPMANN , ANDERSEN ANNE LEE , HOLTMANN ANETTE , HANSEN ANDERS HOLM , SOERENSEN ANDERS MALLING , GOLDBECH ANNE , DE LEON DAEN , KALDOR DITTE KIVSMOSE , SLOEK FRANK ABILGAARD , HUSEMOEN GITTE NYSTRUP , DOLBERG JOHANNES , JENSEN KIM BIRKEBAEK , PETERSEN LENE , NOERREGAARD-MADSEN MADS , GODSKESEN MICHAEL ANDERS , GLAD SANNE SCHROEDER , NEVE SOEREN , THISTED THOMAS , KRONBORG TINE TITILOLA AKINLEM , SAMS CHRISTIAN , FELDING JAKOB , FRESKGAARD PER-OLA , GOULIAEV ALEX HAAHR , PEDERSEN HENRIK
- 申请人： NUEVOLUTION AS , FRANCH THOMAS , LUNDORF MIKKEL DYBRO , JAKOBSEN SOEREN NYBOE , OLSEN EVA KAMPMANN , ANDERSEN ANNE LEE , HOLTMANN ANETTE , HANSEN ANDERS HOLM , SOERENSEN ANDERS MALLING , GOLDBECH ANNE , DE LEON DAEN , KALDOR DITTE KIVSMOSE , SLOEK FRANK ABILGAARD , HUSEMOEN GITTE NYSTRUP , DOLBERG JOHANNES , JENSEN KIM BIRKEBAEK , PETERSEN LENE , NOERREGAARD-MADSEN MADS , GODSKESEN MICHAEL ANDERS , GLAD SANNE SCHROEDER , NEVE SOEREN , THISTED THOMAS , KRONBORG TINE TITILOLA AKINLEM , SAMS CHRISTIAN , FELDING JAKOB , FRESKGAARD PER-OLA , GOULIAEV ALEX HAAHR , PEDERSEN HENRIK
- 专利权人： NUEVOLUTION AS,FRANCH THOMAS,LUNDORF MIKKEL DYBRO,JAKOBSEN SOEREN NYBOE,OLSEN EVA KAMPMANN,ANDERSEN ANNE LEE,HOLTMANN ANETTE,HANSEN ANDERS HOLM,SOERENSEN ANDERS MALLING,GOLDBECH ANNE,DE LEON DAEN,KALDOR DITTE KIVSMOSE,SLOEK FRANK ABILGAARD,HUSEMOEN GITTE NYSTRUP,DOLBERG JOHANNES,JENSEN KIM BIRKEBAEK,PETERSEN LENE,NOERREGAARD-MADSEN MADS,GODSKESEN MICHAEL ANDERS,GLAD SANNE SCHROEDER,NEVE SOEREN,THISTED THOMAS,KRONBORG TINE TITILOLA AKINLEM,SAMS CHRISTIAN,FELDING JAKOB,FRESKGAARD PER-OLA,GOULIAEV ALEX HAAHR,PEDERSEN HENRIK
- 当前专利权人： NUEVOLUTION AS,FRANCH THOMAS,LUNDORF MIKKEL DYBRO,JAKOBSEN SOEREN NYBOE,OLSEN EVA KAMPMANN,ANDERSEN ANNE LEE,HOLTMANN ANETTE,HANSEN ANDERS HOLM,SOERENSEN ANDERS MALLING,GOLDBECH ANNE,DE LEON DAEN,KALDOR DITTE KIVSMOSE,SLOEK FRANK ABILGAARD,HUSEMOEN GITTE NYSTRUP,DOLBERG JOHANNES,JENSEN KIM BIRKEBAEK,PETERSEN LENE,NOERREGAARD-MADSEN MADS,GODSKESEN MICHAEL ANDERS,GLAD SANNE SCHROEDER,NEVE SOEREN,THISTED THOMAS,KRONBORG TINE TITILOLA AKINLEM,SAMS CHRISTIAN,FELDING JAKOB,FRESKGAARD PER-OLA,GOULIAEV ALEX HAAHR,PEDERSEN HENRIK
- 优先权： DKPA200501704 2005-12-01; US74149005 2005-12-02
- 主分类号： C12N15/10
- IPC分类号： C12N15/10 ; C12Q1/68 ; C40B40/06 ; C40B50/06
摘要：
Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).
摘要（中）：
公开了一种获得包含与单链标识符寡核苷酸连接的分子的双功能复合物的方法，其中包含化学反应位点的新生双功能复合物和用于酶标添加的引发位点是a）在化学反应位点与 一种或多种反应物，和b）在起始位点用一种或多种标记反应物的标签进行酶促反应。