基本信息:
- 专利标题: METHOD FOR PERFORMING FED-BATCH OPERATIONS IN SMALL VOLUME REACTORS
- 专利标题(中):在小容量反应器中进行FED-BATCH操作的方法
- 申请号:PCT/US2006/045403 申请日:2006-11-22
- 公开(公告)号:WO2007062218A1 公开(公告)日:2007-05-31
- 发明人: RUSSO, Peter, A. , BERGMAN, Phil , STEBULIS, Matt , HOPE, James , JOHNSON, Timothy, J. , SCHREYER, Howard, Brett
- 申请人: BIOPROCESSORS CORP. , RUSSO, Peter, A. , BERGMAN, Phil , STEBULIS, Matt , HOPE, James , JOHNSON, Timothy, J. , SCHREYER, Howard, Brett
- 申请人地址: 12-A Cabot Road, Woburn, MA 01801 US
- 专利权人: BIOPROCESSORS CORP.,RUSSO, Peter, A.,BERGMAN, Phil,STEBULIS, Matt,HOPE, James,JOHNSON, Timothy, J.,SCHREYER, Howard, Brett
- 当前专利权人: BIOPROCESSORS CORP.,RUSSO, Peter, A.,BERGMAN, Phil,STEBULIS, Matt,HOPE, James,JOHNSON, Timothy, J.,SCHREYER, Howard, Brett
- 当前专利权人地址: 12-A Cabot Road, Woburn, MA 01801 US
- 代理机构: OYER, Timothy, J.
- 优先权: US60/739,689 20051123
- 主分类号: C12P1/00
- IPC分类号: C12P1/00 ; C12M1/00
摘要:
Methods for forming chemical and/or biological products in reactors, and/or analyzing chemical and/or biological interactions in reactors are provided. The methods relate, more specifically, to forming such products and/or carrying out such analyses in small volume reactors with control over overall fluid volume in the reactors. The methods can be used to mimic processes in large scale reactors and/or to obtain reaction or interaction information relevant to large scale reactors (e.g., to adjust/optimize large- scale reactor processes). Advantageously, the methods can allow parameters of small scale reactors to be correlated with those of large scale reactors, where desired.
摘要(中):
提供了在反应器中形成化学和/或生物产物和/或分析反应器中的化学和/或生物相互作用的方法。 所述方法更具体地涉及在具有对反应器中的总流体体积的控制的小体积反应器中形成这样的产物和/或进行这种分析。 该方法可用于模拟大规模反应器中的工艺和/或获得与大规模反应器相关的反应或相互作用信息(例如,调整/优化大规模反应器工艺)。 有利地,如果需要,这些方法可以允许小规模反应器的参数与大规模反应器的参数相关。