基本信息:
- 专利标题： INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1
- 专利标题（中）：11-羟基甾体脱氢酶1型抑制剂
- 申请号：PCT/US2006043951 申请日：2006-11-13
- 公开(公告)号：WO2007061661A3 公开(公告)日：2008-12-11
- 发明人： HENRIKSSON MARTIN , HOMAN EVERT , JOHANSSON LARS , VALLGARDA JERK , WILLIAMS MEREDITH , BERCOT ERIC A , FOTSCH CHRISTOPHER H , LI AIWEN , CAI GUOLIN , HUNGATE RANDALL W , YUAN CHESTER CHENGUANG , TEGLEY CHRISTOPHER , ST JEAN DAVID J JR , HAN NIANHE , HUANG QI , LIU QINGYIAN , BARTBEGER MICHAEL D , MONIZ GEORGE A , FRIZZLE MATTHEW J , MARSHALL TERESA L
- 申请人： AMGEN INC , BIOVITRUM AB , HENRIKSSON MARTIN , HOMAN EVERT , JOHANSSON LARS , VALLGARDA JERK , WILLIAMS MEREDITH , BERCOT ERIC A , FOTSCH CHRISTOPHER H , LI AIWEN , CAI GUOLIN , HUNGATE RANDALL W , YUAN CHESTER CHENGUANG , TEGLEY CHRISTOPHER , ST JEAN DAVID J JR , HAN NIANHE , HUANG QI , LIU QINGYIAN , BARTBEGER MICHAEL D , MONIZ GEORGE A , FRIZZLE MATTHEW J , MARSHALL TERESA L
- 专利权人： AMGEN INC,BIOVITRUM AB,HENRIKSSON MARTIN,HOMAN EVERT,JOHANSSON LARS,VALLGARDA JERK,WILLIAMS MEREDITH,BERCOT ERIC A,FOTSCH CHRISTOPHER H,LI AIWEN,CAI GUOLIN,HUNGATE RANDALL W,YUAN CHESTER CHENGUANG,TEGLEY CHRISTOPHER,ST JEAN DAVID J JR,HAN NIANHE,HUANG QI,LIU QINGYIAN,BARTBEGER MICHAEL D,MONIZ GEORGE A,FRIZZLE MATTHEW J,MARSHALL TERESA L
- 当前专利权人： AMGEN INC,BIOVITRUM AB,HENRIKSSON MARTIN,HOMAN EVERT,JOHANSSON LARS,VALLGARDA JERK,WILLIAMS MEREDITH,BERCOT ERIC A,FOTSCH CHRISTOPHER H,LI AIWEN,CAI GUOLIN,HUNGATE RANDALL W,YUAN CHESTER CHENGUANG,TEGLEY CHRISTOPHER,ST JEAN DAVID J JR,HAN NIANHE,HUANG QI,LIU QINGYIAN,BARTBEGER MICHAEL D,MONIZ GEORGE A,FRIZZLE MATTHEW J,MARSHALL TERESA L
- 优先权： US77597505 2005-11-22
- 主分类号： C07D277/54
- IPC分类号： C07D277/54 ; A61K31/426 ; A61K31/427 ; A61K31/428 ; A61P3/04 ; A61P3/06 ; A61P3/10 ; A61P9/12 ; A61P19/10 ; A61P25/24 ; C07D277/60 ; C07D417/04 ; C07D417/06 ; C07D417/12 ; C07D417/14
摘要：
The present invention relates to thiazolinones and also to pharmaceutical compositions comprising the compounds, as well as methods of use of the compounds for treatment of disorders associated with human 11-ß-hydroxysteroid dehydrogenase type 1 enzyme and for the preparation of a medicament which acts on the human 11- ß-hydroxysteroid dehydrogenase type 1 enzyme.
摘要（中）：
本发明涉及噻唑啉酮以及包含该化合物的药物组合物，以及该化合物用于治疗与人类11-羟基类固醇脱氢酶1型酶有关的病症的用途的方法以及用于制备作用于 人类11-羟基类固醇脱氢酶1型酶。
公开/授权文献:
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D277/00 | 杂环化合物，含有1,3-噻唑或氢化1,3-噻唑环 |
| --------C07D277/02 | .不和其他环稠合 |
| ----------C07D277/04 | ..环原子间或环原子与非环原子间没有双键 |
| ------------C07D277/22 | ...仅有氢原子、烃基或取代烃基，直接连在环碳原子上 |
| --------------C07D277/54 | ....氮和氧原子或氮和硫原子 |