基本信息:
- 专利标题： ADRENERGIC RECEPTOR ANTAGONISTS
- 申请号：PCT/IB2006/051392 申请日：2006-05-03
- 公开(公告)号：WO2006117760A1 公开(公告)日：2006-11-09
- 发明人： SARMA, Pakala, Kumara, Savithru , SHARMA, Somesh , DHARMARAJAN, Sankaranarayanan , SHELKE, Sandeep Y. , PAL, Arani , KONDASKAR, Atul , GUPTA, Praful , CHUGH, Anita , TIWARI, Atul , NANDA, Kamna
- 申请人： RANBAXY LABORATORIES LIMITED , SARMA, Pakala, Kumara, Savithru , SHARMA, Somesh , DHARMARAJAN, Sankaranarayanan , SHELKE, Sandeep Y. , PAL, Arani , KONDASKAR, Atul , GUPTA, Praful , CHUGH, Anita , TIWARI, Atul , NANDA, Kamna
- 申请人地址： Plot No. 90, Sector - 32, Gurgaon, Haryana 122 001 IN
- 专利权人： RANBAXY LABORATORIES LIMITED,SARMA, Pakala, Kumara, Savithru,SHARMA, Somesh,DHARMARAJAN, Sankaranarayanan,SHELKE, Sandeep Y.,PAL, Arani,KONDASKAR, Atul,GUPTA, Praful,CHUGH, Anita,TIWARI, Atul,NANDA, Kamna
- 当前专利权人： RANBAXY LABORATORIES LIMITED,SARMA, Pakala, Kumara, Savithru,SHARMA, Somesh,DHARMARAJAN, Sankaranarayanan,SHELKE, Sandeep Y.,PAL, Arani,KONDASKAR, Atul,GUPTA, Praful,CHUGH, Anita,TIWARI, Atul,NANDA, Kamna
- 当前专利权人地址： Plot No. 90, Sector - 32, Gurgaon, Haryana 122 001 IN
- 代理机构： RANBAXY LABORATORIES LIMITED
- 优先权： IN1099/DEL/2005 20050503
- 主分类号： C07D401/06
- IPC分类号： C07D401/06 ; C07D403/06 ; C07D413/06 ; C07D417/06 ; A61K31/53 ; A61K31/536 ; A61K31/5415 ; A61P13/00
摘要：
The present invention relates to α 1a and/or α 1b adrenergic receptor antagonists, which can be used to treat a disease or disorder mediated through α 1a and/or α 1b adrenergic receptors. Compounds and pharmaceutical compositions disclosed herein can be used to treat benign prostatic hyperplasia (BPH) and related symptoms thereof. Further, such compounds can be used to treat lower urinary tract symptoms that may or may not be associated with BPH. The present invention also relates to processes to prepare the disclosed compounds, pharmaceutical compositions thereof, and methods of treating BPH or related symptoms thereof.
摘要（中）：
本发明涉及可用于治疗通过1a介导的疾病或病症的α1a1和/或1b2肾上腺素能受体拮抗剂和/或1b 1b肾上腺素能受体。 本文公开的化合物和药物组合物可用于治疗良性前列腺增生（BPH）及其相关症状。 此外，这些化合物可用于治疗可能与也可能不伴有BPH的下尿路症状。 本发明还涉及制备所公开的化合物的方法，其药物组合物，以及治疗BPH或其相关症状的方法。
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D401/00 | 杂环化合物，含有两个或更多个杂环，以氮原子作为仅有的杂环原子，至少有1个环是仅含有1个氮原子的六元环 |
| --------C07D401/02 | .含有两个杂环 |
| ----------C07D401/06 | ..被仅含脂族碳原子的碳链连接的 |