基本信息:
- 专利标题： NOVEL COMPOUNDS USEFUL FOR BRADYKININ B1 RECEPTOR ANTAGONISM
- 专利标题（中）：新型化合物对BRADYKININ B1受体拮抗剂有用
- 申请号：PCT/US2005/046785 申请日：2005-12-21
- 公开(公告)号：WO2006071775A2 公开(公告)日：2006-07-06
- 发明人： TUNG, Jay, S. , DRESSEN, Darren, D. , NETIZ, R., Jeffrey , PLEISS, Michael, A.
- 申请人： ELAN PHARMACEUTICALS, INC. , TUNG, Jay, S. , DRESSEN, Darren, D. , NETIZ, R., Jeffrey , PLEISS, Michael, A.
- 申请人地址： 800 Gateway Boulevard, South San Francisco, California 94080 US
- 专利权人： ELAN PHARMACEUTICALS, INC.,TUNG, Jay, S.,DRESSEN, Darren, D.,NETIZ, R., Jeffrey,PLEISS, Michael, A.
- 当前专利权人： ELAN PHARMACEUTICALS, INC.,TUNG, Jay, S.,DRESSEN, Darren, D.,NETIZ, R., Jeffrey,PLEISS, Michael, A.
- 当前专利权人地址： 800 Gateway Boulevard, South San Francisco, California 94080 US
- 代理机构： GARRETT, Arthur, S.
- 优先权： US60/640,021 20041229
摘要：
Disclosed are compounds that are bradykinin B 1 receptor antagonists and are useful for treating diseases, or relieving adverse symptoms associated with disease conditions, in mammals mediated by bradykinin B 1 receptor. Certain of the compounds exhibit increased potency and are also expected to exhibit increased duration of action.
摘要（中）：
公开了缓激肽B 1受体拮抗剂的化合物，并且可用于治疗由缓激肽B 1受体介导的哺乳动物中疾病或与疾病状况相关的不良症状。 某些化合物表现出更高的效力，并且还预期表现出增加的作用持续时间。