发明申请
WO2006071564A3 AMINIUM SALTS OF 1,2,3-TRIAZOLES AS PRODRUGS OF DRUGS INCLUDING ANTIVIRAL AGENTS
审中-公开
基本信息:
- 专利标题： AMINIUM SALTS OF 1,2,3-TRIAZOLES AS PRODRUGS OF DRUGS INCLUDING ANTIVIRAL AGENTS
- 申请号：PCT/US2005/045591 申请日：2005-12-15
- 公开(公告)号：WO2006071564A3 公开(公告)日：2006-07-06
- 发明人： KADOW, John, F. , REGUEIRO-REN, Alicia
- 申请人： BRISTOL-MYERS SQUIBB COMPANY , KADOW, John, F. , REGUEIRO-REN, Alicia
- 申请人地址： Route 206 And Province Line Road, Princeton, New Jersey 08543-4000 US
- 专利权人： BRISTOL-MYERS SQUIBB COMPANY,KADOW, John, F.,REGUEIRO-REN, Alicia
- 当前专利权人： BRISTOL-MYERS SQUIBB COMPANY,KADOW, John, F.,REGUEIRO-REN, Alicia
- 当前专利权人地址： Route 206 And Province Line Road, Princeton, New Jersey 08543-4000 US
- 代理机构： CHIN, Jennifer, T. et al.
- 优先权： US60/640,185 20041229
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K31/437 ; A61P31/18
摘要：
This disclosure provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the disclosure is concerned with new aminium salts of 1,2,3-triazoles which can be used as prodrugs to improve the solubility or pharmaceutical properties of 1,2,3-triazole containing compounds. More particularly, the present disclosure relates to compounds containing N-aminium-1,2,3-triazoles that are useful as antiviral agents and specifically for the treatment of HIV and AIDS.
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D471/00 | 在稠环系中含有氮原子作为仅有的杂环原子、其中至少1个环是含有1个氮原子的六元环的杂环化合物，C07D451/00至C07D463/00不包括的 |
| --------C07D471/02 | .在稠环系中含两个杂环 |
| ----------C07D471/04 | ..邻位稠环系 |