发明申请
WO2006034277A1 BICYCLIC COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF
审中-公开
基本信息:
- 专利标题： BICYCLIC COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF
- 专利标题（中）：抑制β-分泌酶活性的双环化合物及其使用方法
- 申请号：PCT/US2005/033678 申请日：2005-09-19
- 公开(公告)号：WO2006034277A1 公开(公告)日：2006-03-30
- 发明人： GHOSH, Arun , LEI, Hui , DEVASAMUDRAM, Thippeswamy , LIU, Chunfeng , TANG, Jordan , BILCER, Geoffrey
- 申请人： ZAPAQ, INC. , THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS , OKLAHOMA MEDICAL RESEARCH FOUNDATION , GHOSH, Arun , LEI, Hui , DEVASAMUDRAM, Thippeswamy , LIU, Chunfeng , TANG, Jordan , BILCER, Geoffrey
- 申请人地址： 1050 Winter Street, Suite 1000, Waltham, MA 02451 US
- 专利权人： ZAPAQ, INC.,THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS,OKLAHOMA MEDICAL RESEARCH FOUNDATION,GHOSH, Arun,LEI, Hui,DEVASAMUDRAM, Thippeswamy,LIU, Chunfeng,TANG, Jordan,BILCER, Geoffrey
- 当前专利权人： ZAPAQ, INC.,THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS,OKLAHOMA MEDICAL RESEARCH FOUNDATION,GHOSH, Arun,LEI, Hui,DEVASAMUDRAM, Thippeswamy,LIU, Chunfeng,TANG, Jordan,BILCER, Geoffrey
- 当前专利权人地址： 1050 Winter Street, Suite 1000, Waltham, MA 02451 US
- 代理机构： JENKINS, Kenneth, E. et al.
- 优先权： US60/610,874 20040917
- 主分类号： C07D277/28
- IPC分类号： C07D277/28 ; C07D263/32 ; C07C233/64 ; C07D305/06 ; C07D213/38 ; C07D207/09 ; C07D263/20 ; C07D307/52 ; C07D213/40 ; C07D205/04 ; C07D241/12 ; C07D233/64
摘要：
The present invention provides bicyclic beta-secretase inhibitors and methods for their use, including methods of treating of Alzheimer’s disease.
摘要（中）：
本发明提供双环β-分泌酶抑制剂及其使用方法，包括治疗阿尔茨海默氏病的方法。
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D277/00 | 杂环化合物，含有1,3-噻唑或氢化1,3-噻唑环 |
| --------C07D277/02 | .不和其他环稠合 |
| ----------C07D277/04 | ..环原子间或环原子与非环原子间没有双键 |
| ------------C07D277/22 | ...仅有氢原子、烃基或取代烃基，直接连在环碳原子上 |
| --------------C07D277/28 | ....被氮原子取代的基 |