A system (10) is disclosed for accomplishing the percutaneous fixation and stabilization of a fracture with a spanning, expandable structural frame (20) placed in the intramedullary canal (120) of the bone (100). The system in one embodiment includes a column of surgical fluid (40) such as bone cement, within which the structural frame acts as a reinforcing cage, and a sheath (30) positioned at the fracture site and at least partially surrounding the frame and fluid. The fluid may be supported by a restrictor and may be agitated with a vibrating probe to remove entrapped air. The structural frame may be self-expanding or opened by an internal force, and it may be retrievable. The frame, fluid, or sheath may contain antibiotics, pharmaceuticals, or other therapeutic compounds to be delivered to the fracture site. This abstract is provided to inform the reader about the subject matter of the application, not to demarcate the meaning or scope of the claims. The system is disclosed for accomplishing the percutaneous fixation and stabilization of a fracture with a spanning, expandable structural frame place in the intramedullary canal of the bone. The system is one embodiment includes a column of surgical fluid such as bone cement, within which the structural frame acts as reinforcing cage, and a sheath positioned at the fracture site and at least partially surrounding the frame and fluid. The fluid may be supported by a restrictor and may be agitated with a vibrating probe to remove entrapped air. The structural frame may be self-expanding or opened by an internal force, and it may be retrievable. The frame, fluid, or sheath may contain antibiotics, pharmaceuticals, or other therapeutic compounds to be delivered to the fracture site.