发明申请
WO2005087215A1 SUBSTITUTED UREA AND CARBAMATE, PHENACYL-2-HYDROXY-3-DIAMINOALKANE, AND BENZAMIDE-2-HYDROXY-3-DIAMINOALKANE ASPARTYL-PROTEASE INHIBITORS
审中-公开
基本信息:
- 专利标题： SUBSTITUTED UREA AND CARBAMATE, PHENACYL-2-HYDROXY-3-DIAMINOALKANE, AND BENZAMIDE-2-HYDROXY-3-DIAMINOALKANE ASPARTYL-PROTEASE INHIBITORS
- 专利标题（中）：取代的尿素和卡巴酸盐，PHENACYL-2-羟基-3-二氨基壬酸和苯甲酰-2-羟基-3-二氨基甘氨酸ASPARTYL-PROTEASE抑制剂
- 申请号：PCT/US2005/007775 申请日：2005-03-09
- 公开(公告)号：WO2005087215A1 公开(公告)日：2005-09-22
- 发明人： JOHN, Varghese , MAILLARD, Michel , TUCKER, John , AQUINO, Jose , HOM, Roy , TUNG, Jay , DRESSEN, Darren , SHAH, Neerav , NEITZ, R., Jeffrey
- 申请人： ELAN PHARMACEUTICALS, INC. , JOHN, Varghese , MAILLARD, Michel , TUCKER, John , AQUINO, Jose , HOM, Roy , TUNG, Jay , DRESSEN, Darren , SHAH, Neerav , NEITZ, R., Jeffrey
- 申请人地址： 800 Gateway Boulevard, South San Francisco, CA 94080-7085 US
- 专利权人： ELAN PHARMACEUTICALS, INC.,JOHN, Varghese,MAILLARD, Michel,TUCKER, John,AQUINO, Jose,HOM, Roy,TUNG, Jay,DRESSEN, Darren,SHAH, Neerav,NEITZ, R., Jeffrey
- 当前专利权人： ELAN PHARMACEUTICALS, INC.,JOHN, Varghese,MAILLARD, Michel,TUCKER, John,AQUINO, Jose,HOM, Roy,TUNG, Jay,DRESSEN, Darren,SHAH, Neerav,NEITZ, R., Jeffrey
- 当前专利权人地址： 800 Gateway Boulevard, South San Francisco, CA 94080-7085 US
- 代理机构： GARRETT, Arthur, S.
- 优先权： US60/551,192 20040309; US60/575,829 20040602; US60/591,857 20040729; US60/622,589 20041028
- 主分类号： A61K31/16
- IPC分类号： A61K31/16
摘要：
The invention relates to acetyl 2-hydroxy-1,3-diaminospirocyclohexanes and derivatives thereof that are useful in treating at least one disease, disorder, and condition associated with amyloidosis. Amyloidosis refers to a collection of diseases, disorders, and condition associated with abnormal deposition of A-beta protein.
摘要（中）：
本发明涉及可用于治疗与淀粉样变性相关的至少一种疾病，病症和病症的乙酰基2-羟基-1,3-二氨基螺环己烷及其衍生物。 淀粉样变性是指与A-β蛋白异常沉积相关的疾病，病症和病症的集合。
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K31/00 | 含有机有效成分的医药配制品 |
| --------A61K31/16 | .酰胺，例如异羟肟酸 |