发明申请
WO2005052146A8 SERINE PROTEASES, NUCLEIC ACIDS ENCODING SERINE ENZYMES AND VECTORS AND HOST CELLS INCORPORATING SAME
审中-公开
基本信息:
- 专利标题： SERINE PROTEASES, NUCLEIC ACIDS ENCODING SERINE ENZYMES AND VECTORS AND HOST CELLS INCORPORATING SAME
- 专利标题（中）：丝氨酸蛋白酶，核酸编码丝氨酸酶和载体和宿主细胞
- 申请号：PCT/US2004039066 申请日：2004-11-19
- 公开(公告)号：WO2005052146A8 公开(公告)日：2006-08-24
- 发明人： JONES BRIAN EDWARD , KOLKMAN MARC , LEEFLANG CHRIS , OH HIROSHI , POULOSE AYROOKARAN J , SADLOWSKI EUGENE S , SHAW ANDREW , VAN DER KLEIJ WILHELMUS A H , VAN MARREWIJK LEO
- 申请人： GENENCOR INT , PROCTER & GAMBLE , JONES BRIAN EDWARD , KOLKMAN MARC , LEEFLANG CHRIS , OH HIROSHI , POULOSE AYROOKARAN J , SADLOWSKI EUGENE S , SHAW ANDREW , VAN DER KLEIJ WILHELMUS A H , VAN MARREWIJK LEO
- 专利权人： GENENCOR INT,PROCTER & GAMBLE,JONES BRIAN EDWARD,KOLKMAN MARC,LEEFLANG CHRIS,OH HIROSHI,POULOSE AYROOKARAN J,SADLOWSKI EUGENE S,SHAW ANDREW,VAN DER KLEIJ WILHELMUS A H,VAN MARREWIJK LEO
- 当前专利权人： GENENCOR INT,PROCTER & GAMBLE,JONES BRIAN EDWARD,KOLKMAN MARC,LEEFLANG CHRIS,OH HIROSHI,POULOSE AYROOKARAN J,SADLOWSKI EUGENE S,SHAW ANDREW,VAN DER KLEIJ WILHELMUS A H,VAN MARREWIJK LEO
- 优先权： US52360903 2003-11-19
- 主分类号： C11D3/386
- IPC分类号： C11D3/386 ; C12N9/52 ; C12N9/64
摘要：
The present invention provides novel serine proteases, novel genetic material encoding these enzymes, and proteolytic proteins obtained from Micrococcineae spp., including but not limited to Cellulomonas spp. and variant proteins developed therefrom. In particular, the present invention provides protease compositions obtained from a Cellulomonas spp, DNA encoding the protease, vectors comprising the DNA encoding the protease, host cells transformed with the vector DNA, and an enzyme produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising protease(s) obtained from a Micrococcineae spp., including but not limited to Cellulomonas spp. In alternative embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These mutant proteases also find use in numerous applications.
摘要（中）：
本发明提供了新的丝氨酸蛋白酶，编码这些酶的新型遗传物质，以及从微球菌属（Micrococcineae spp。）获得的蛋白水解蛋白，包括但不限于纤维单胞菌属（Cellulomonas spp） 和从其开发的变体蛋白质。 特别地，本发明提供了从纤维单胞菌属（Splulomonas spp）获得的蛋白酶组合物，编码蛋白酶的DNA，包含编码蛋白酶的载体，载体DNA转化的宿主细胞和由宿主细胞产生的酶。 本发明还提供了清洁组合物（例如洗涤剂组合物），动物饲料组合物，以及包含从微球菌（Micrococcineae spp。）获得的蛋白酶的纺织和皮革加工组合物，其包括但不限于纤维单胞菌属（Cellulomonas spp） 在替代实施方案中，本发明提供衍生自本文所述的野生型蛋白酶的突变体（即，变体）蛋白酶。 这些突变型蛋白酶也可用于许多应用。
公开/授权文献:
IPC结构图谱:
| C | 化学；冶金 |
| --C11 | 动物或植物油、脂、脂肪物质或蜡；由此制取的脂肪酸；洗涤剂；蜡烛 |
| ----C11D | 洗涤剂组合物；用单一物质作为洗涤剂；皂或制皂；树脂皂；甘油的回收 |
| ------C11D3/00 | 包括在C11D1/00组内之洗涤组合物的其他配料成分 |
| --------C11D3/02 | .无机化合物 |
| ----------C11D3/38 | ..含无明确规定组分的产物 |
| ------------C11D3/386 | ...含酶的制品 |