基本信息:
- 专利标题： PROCESS FOR PREPARING ACYLPHOSPHANES AND DERIVATIVES THEREOF
- 专利标题（中）：制备其中的酰亚胺及其衍生物的方法
- 申请号：PCT/EP2004/051427 申请日：2004-07-09
- 公开(公告)号：WO2005014605A1 公开(公告)日：2005-02-17
- 发明人： SOMMERLADE, Reinhard H. , BOULMAÂZ, Souâd , WOLF, Jean-Pierre , GEIER, Jens , GRÜTZMACHER, Hansjörg , SCHERER, Markus , SCHÖNBERG, Hartmut , STEIN, Daniel , MURER, Peter , BURKHARDT, Stephan
- 申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , SOMMERLADE, Reinhard H. , BOULMAÂZ, Souâd , WOLF, Jean-Pierre , GEIER, Jens , GRÜTZMACHER, Hansjörg , SCHERER, Markus , SCHÖNBERG, Hartmut , STEIN, Daniel , MURER, Peter , BURKHARDT, Stephan
- 申请人地址： Klybeckstrasse 141, CH-4057 Basel CH
- 专利权人： CIBA SPECIALTY CHEMICALS HOLDING INC.,SOMMERLADE, Reinhard H.,BOULMAÂZ, Souâd,WOLF, Jean-Pierre,GEIER, Jens,GRÜTZMACHER, Hansjörg,SCHERER, Markus,SCHÖNBERG, Hartmut,STEIN, Daniel,MURER, Peter,BURKHARDT, Stephan
- 当前专利权人： CIBA SPECIALTY CHEMICALS HOLDING INC.,SOMMERLADE, Reinhard H.,BOULMAÂZ, Souâd,WOLF, Jean-Pierre,GEIER, Jens,GRÜTZMACHER, Hansjörg,SCHERER, Markus,SCHÖNBERG, Hartmut,STEIN, Daniel,MURER, Peter,BURKHARDT, Stephan
- 当前专利权人地址： Klybeckstrasse 141, CH-4057 Basel CH
- 代理机构： CIBA SPECIALTY CHEMICALS HOLDING INC.
- 优先权： EP03405551.7 20030718
- 主分类号： C07F9/50
- IPC分类号： C07F9/50
摘要：
The present invention relates to a new, selective process for the preparation of mono- and bisacylphosphanes of formula (I) n and m are each independently of the other 1 or 2; R 1 , if n = 1, is e.g. phenyl R 1 , if n = 2, is e.g. C 1 -C 18 alkylene or phenylene; R 2 is e. g. C 1 -C 18 alkyl, phenyl or substituted phenyl; R 3 is e. g. C 1 -C 18 alkyl, by (1) reacting a phosphorous halide of formula Ila or a phosphorous halide oxide of formula (Ilb) or a phosphorous halide sulfide of formula (IIc) with an alkali metal in a solvent in the presence of a proton source; (2) subsequent reaction with m acid halides of formula (III) An oxidation step may follow to obtain mono- and bisacylphosphane oxides or mono-and bisacylphosphane sulfides.
摘要（中）：
本发明涉及制备式（I）的单 - 和双酰基磷烷的新的选择性方法，n和m各自独立地为1或2; R1，如果n = 1，则为例如 苯基R1，如果n = 2，是例如。 C1-C18亚烷基或亚苯基; R2是e。 G。 C 1 -C 18烷基，苯基或取代的苯基; R3是e。 G。 通过（1）在溶剂中在质子源的存在下使式IIa的卤化磷或式（IIb）的卤化磷或式（IIc）的卤化磷化物与碱金属在碱性溶剂中反应; （2）随后与式（III）的酰卤反应可以进行氧化步骤以获得单酰基和双酰基氧化膦或单酰基和双酰基磷烷硫化物。