发明申请
WO2004074508A2 METHOD OF VISUALIZATION AND QUANTIFICATION OF BIOPOLYMER MOLECULES IMMOBILIZED ON SOLID SUPPORT
审中-公开
基本信息:
- 专利标题: METHOD OF VISUALIZATION AND QUANTIFICATION OF BIOPOLYMER MOLECULES IMMOBILIZED ON SOLID SUPPORT
- 专利标题(中):在固体支持下固定生物聚合物分子的可视化和定量方法
- 申请号:PCT/US2004/003850 申请日:2004-02-11
- 公开(公告)号:WO2004074508A2 公开(公告)日:2004-09-02
- 发明人: GOLOVLEV, Valeri V. , SUN, Ye , MCCANN, Michael P. , FAN, Wen-Hua
- 申请人: GOLOVLEV, Valeri V. , SUN, Ye , MCCANN, Michael P. , FAN, Wen-Hua
- 申请人地址: 107 Canterbury Rd., Oak Ridge, Tennessee 37830 US
- 专利权人: GOLOVLEV, Valeri V.,SUN, Ye,MCCANN, Michael P.,FAN, Wen-Hua
- 当前专利权人: GOLOVLEV, Valeri V.,SUN, Ye,MCCANN, Michael P.,FAN, Wen-Hua
- 当前专利权人地址: 107 Canterbury Rd., Oak Ridge, Tennessee 37830 US
- 代理机构: LUKON, Michael T.
- 优先权: US60/448,175 20030215
- 主分类号: C12Q
- IPC分类号: C12Q
摘要:
A method and kit are provided for visualization of a latent pattern of molecular structures on a substrate surface. The method is comprised of developing the substrate in a solution of colloidal particles. A detectable change on the substrate surface is brought about as a result of the precipitation of the colloidal particles. The invention also provides compositions and kits for practicing the method of the present invention. Further, the invention provides methods of capturing images of the substrate surface for visualization and quantification of the molecular structures.
摘要(中):
提供了一种方法和试剂盒,用于在基底表面上可视化分子结构的潜在图案。 该方法包括在胶体颗粒溶液中显影底物。 作为胶体颗粒沉淀的结果,引起基板表面上的可检测的变化。 本发明还提供了用于实施本发明方法的组合物和试剂盒。 此外,本发明提供了捕获衬底表面的图像以便可视化和定量分子结构的方法。