基本信息:
- 专利标题: TRICYCLIC STEROID HORMONE NUCLEAR RECEPTOR MODULATORS
- 申请号:PCT/US2003/016213 申请日:2003-06-13
- 公开(公告)号:WO2004052847A2 公开(公告)日:2004-06-24
- 发明人: COGHLAN, Michael, Joseph , GREEN, Jonathan, Edward , GRESE, Timothy, Alan , JADHAV, Prabhakar, Kondaji , MATTHEWS, Donald, Paul , STEINBERG, Mitchell, Irvin , FALES, Kevin, Robert , BELL, Michael, Gregory
- 申请人: ELI LILLY AND COMPANY , COGHLAN, Michael, Joseph , GREEN, Jonathan, Edward , GRESE, Timothy, Alan , JADHAV, Prabhakar, Kondaji , MATTHEWS, Donald, Paul , STEINBERG, Mitchell, Irvin , FALES, Kevin, Robert , BELL, Michael, Gregory
- 申请人地址: Lilly Corporate Center, Indianapolis, IN 46285 US
- 专利权人: ELI LILLY AND COMPANY,COGHLAN, Michael, Joseph,GREEN, Jonathan, Edward,GRESE, Timothy, Alan,JADHAV, Prabhakar, Kondaji,MATTHEWS, Donald, Paul,STEINBERG, Mitchell, Irvin,FALES, Kevin, Robert,BELL, Michael, Gregory
- 当前专利权人: ELI LILLY AND COMPANY,COGHLAN, Michael, Joseph,GREEN, Jonathan, Edward,GRESE, Timothy, Alan,JADHAV, Prabhakar, Kondaji,MATTHEWS, Donald, Paul,STEINBERG, Mitchell, Irvin,FALES, Kevin, Robert,BELL, Michael, Gregory
- 当前专利权人地址: Lilly Corporate Center, Indianapolis, IN 46285 US
- 代理机构: WILSON, Alexander
- 优先权: US60/391,992 20020626
- 主分类号: C07C311/00
- IPC分类号: C07C311/00
摘要:
The present invention relates to methods of treating pathological disorders susceptible to steroid hormone nuclear receptor modulation comprising administering to a patient in need thereof an effective amount of a compound of the formula (I): or a pharmaceutically acceptable salt thereof. In addition, the present invention provides novel pharmaceutical compounds of Formula (I), including the pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions which comprise as an active ingredient a compound of Formula (I).
摘要(中):
本发明涉及治疗对类固醇激素核受体调节敏感的病理学障碍的方法,包括向有需要的患者施用有效量的式(I)化合物或其药学上可接受的盐。 此外,本发明提供新的式(I)的药物化合物,包括其药学上可接受的盐,以及包含作为活性成分的式(I)的化合物的药物组合物。
IPC结构图谱:
C | 化学;冶金 |
--C07 | 有机化学 |
----C07C | 无环或碳环化合物 |
------C07C311/00 | 磺酰胺,即磺基的单键氧原子被不属于硝基或亚硝基的氮原子取代的化合物 |