基本信息:
- 专利标题： MAP2K6 AS MODIFIER OF BRANCHING MORPHOGENENSIS AND METHODS OF USE
- 专利标题（中）：MAP2K6作为分子生物学的改良剂及其使用方法
- 申请号：PCT/US2003/033489 申请日：2003-10-22
- 公开(公告)号：WO2004037986A2 公开(公告)日：2004-05-06
- 发明人： PLOWMAN, Gregory, D. , KARIM, Felix, D. , SWIMMER, Candace , HABECK, Hinrich, Alexander , KOBLIZEK, Thomas, I. , SCHULTE-MERKER, Stefan , LANGHEINRICH, Ulrike , STOTT, Gordon, Mark , TROWE, Torsten , VOGEL, Andreas, Michael , ODENTHAL, Joerg, Heinrich , SCHEEL, Jochen, Konrad , WILL, Torsten, Tilmann , JIN, Yisheng
- 申请人： EXELIXIS, INC. , PLOWMAN, Gregory, D. , KARIM, Felix, D. , SWIMMER, Candace , HABECK, Hinrich, Alexander , KOBLIZEK, Thomas, I. , SCHULTE-MERKER, Stefan , LANGHEINRICH, Ulrike , STOTT, Gordon, Mark , TROWE, Torsten , VOGEL, Andreas, Michael , ODENTHAL, Joerg, Heinrich , SCHEEL, Jochen, Konrad , WILL, Torsten, Tilmann , JIN, Yisheng
- 申请人地址： P.O. Box 511, 170 Harbor Way, South San Francisco, CA 94083-0511 US
- 专利权人： EXELIXIS, INC.,PLOWMAN, Gregory, D.,KARIM, Felix, D.,SWIMMER, Candace,HABECK, Hinrich, Alexander,KOBLIZEK, Thomas, I.,SCHULTE-MERKER, Stefan,LANGHEINRICH, Ulrike,STOTT, Gordon, Mark,TROWE, Torsten,VOGEL, Andreas, Michael,ODENTHAL, Joerg, Heinrich,SCHEEL, Jochen, Konrad,WILL, Torsten, Tilmann,JIN, Yisheng
- 当前专利权人： EXELIXIS, INC.,PLOWMAN, Gregory, D.,KARIM, Felix, D.,SWIMMER, Candace,HABECK, Hinrich, Alexander,KOBLIZEK, Thomas, I.,SCHULTE-MERKER, Stefan,LANGHEINRICH, Ulrike,STOTT, Gordon, Mark,TROWE, Torsten,VOGEL, Andreas, Michael,ODENTHAL, Joerg, Heinrich,SCHEEL, Jochen, Konrad,WILL, Torsten, Tilmann,JIN, Yisheng
- 当前专利权人地址： P.O. Box 511, 170 Harbor Way, South San Francisco, CA 94083-0511 US
- 代理机构： SHAYESTEH, Laleh
- 优先权： US60/420,554 20021023
- 主分类号： C12N
- IPC分类号： C12N
摘要：
Human MAP2K6 genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis funcion. Methods for identifying modulators of branching morphogenesis, comprising screening for agents that modulate the activity of MAP2K6 are provided.
摘要（中）：
人MAP2K6基因被鉴定为分支形态发生的调节剂，因此是与缺陷支链形态发生功能相关的病症的治疗靶点。 提供了用于鉴定分支形态发生调节剂的方法，包括筛选调节MAP2K6活性的试剂。