基本信息:
- 专利标题： PROTEIN C POLYMORPHISMS USEFUL AS AN INDICATOR OF PATIENT OUTCOME
- 专利标题（中）：蛋白C多态性作为患者观察指标有用
- 申请号：PCT/CA2003/000751 申请日：2003-05-28
- 公开(公告)号：WO2003100090A2 公开(公告)日：2003-12-04
- 发明人： RUSSELL, James, A. , WALLEY, Keith, R.
- 申请人： THE UNIVERSITY OF BRITISH COLUMBIA , RUSSELL, James, A. , WALLEY, Keith, R.
- 申请人地址： University Liaison Office, IRC Room 331, 2194 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3 CA
- 专利权人： THE UNIVERSITY OF BRITISH COLUMBIA,RUSSELL, James, A.,WALLEY, Keith, R.
- 当前专利权人： THE UNIVERSITY OF BRITISH COLUMBIA,RUSSELL, James, A.,WALLEY, Keith, R.
- 当前专利权人地址： University Liaison Office, IRC Room 331, 2194 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3 CA
- 代理机构： ROBINSON, Christopher, J.
- 优先权： US60/383,128 20020528
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
The invention provides methods and kits for obtaining a prognosis for a patient having or at risk of developing an inflammatory condition. The method generally comprises determining a protein C promoter genotype of a patient for a polymorphism in the protein C promoter region of the patient, comparing the determined genotype with known genotypes for the polymorphism that correspond with the ability of the patient to recover from the inflammatory condition and identifying patients based on their prognosis. The invention also provides for methods of identifying other polymorphisms that correspond with the ability of the patient to recover from the inflammatory condition.
摘要（中）：
本发明提供了用于获得具有或具有发展炎性病症风险的患者的预后的方法和试剂盒。 该方法通常包括确定患者的蛋白C启动子基因型，用于患者的蛋白C启动子区域中的多态性，将确定的基因型与已知基因型与多态性相比较，其与患者从炎性病症恢复的能力相对应 并根据患者的预后鉴别患者。 本发明还提供了鉴定与患者从炎性病症恢复的能力相对应的其他多态性的方法。
公开/授权文献:
- WO2003100090A3 PROTEIN C POLYMORPHISMS 公开/授权日：2003-12-04