基本信息:
- 专利标题： COMPOSITIONS AND METHODS FOR THE TREATMENT OF ANORECTAL DISORDERS
- 申请号：PCT/US2003/007106 申请日：2003-03-05
- 公开(公告)号：WO2003075851A3 公开(公告)日：2003-09-18
- 发明人： PARKS, Thomas, P. , MAK, Vivien, H., W. , LEE, Jung-Chung , LEE, Charles , GRAYSON, Stephen
- 申请人： CELLEGY PHARMACEUTICALS, INC. , PARKS, Thomas, P. , MAK, Vivien, H., W. , LEE, Jung-Chung , LEE, Charles , GRAYSON, Stephen
- 申请人地址： 349 Oyster Point Boulevard Suite 200 South San Francisco, CA 94080 US
- 专利权人： CELLEGY PHARMACEUTICALS, INC.,PARKS, Thomas, P.,MAK, Vivien, H., W.,LEE, Jung-Chung,LEE, Charles,GRAYSON, Stephen
- 当前专利权人： CELLEGY PHARMACEUTICALS, INC.,PARKS, Thomas, P.,MAK, Vivien, H., W.,LEE, Jung-Chung,LEE, Charles,GRAYSON, Stephen
- 当前专利权人地址： 349 Oyster Point Boulevard Suite 200 South San Francisco, CA 94080 US
- 代理机构： MYCROFT, Frank, J. et al.
- 优先权： US60/362,698 20020306
- 主分类号： A61K31/35
- IPC分类号： A61K31/35 ; A61K31/56 ; A61K31/165
摘要：
Compositions and methods for the treatment of patients with anorectal disorders including colostomy are provided in which certain compounds including, but not limited to, NO donors, calcium channel blockers, cholinergic modulators (including acetylcholine storage blocking agents and acetylcholine vesicle storage blocking agents), α-adrenergic receptor antagonists (including α 1 -adrenergic antagonists and α 2 -adrenergic antagonists), β-adrenergic receptor agonists (including β 2 -adrenergic antagonists and β 3 -adrenergic antagonists), phosphodiesterase inhibitors, cAMP-dependent protein kinase activators (e.g., cAMP mimetics), superoxide scavengers, potassium channel activators (including ATP-sensitive potassium channel activators and activators of the Maxi-K channels), estrogen-like compounds, testosterone-like compounds, benzodiazepines, adrenergic nerve inhibitors, antidiarrheal agents, HMG-CoA reductase inhibitors, smooth muscle relaxants, adenosine receptor modulators, adenylyl cyclase activators, endothelin receptor antagonists, bisphosphonates, cGMP-dependent protein kinase activators (e.g., cGMP mimetics), and combinations thereof are used.
公开/授权文献:
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K31/00 | 含有机有效成分的医药配制品 |
| --------A61K31/33 | .杂环化合物 |
| ----------A61K31/335 | ..仅有氧作为环杂原子的，例如制霉色基素 |
| ------------A61K31/35 | ...有仅以1个氧作为环杂原子的六元环的 |