基本信息:
- 专利标题： MBCATS AS MODIFIERS OF THE BETA-CATENIN PATHWAY AND METHODS OF USE
- 申请号：PCT/US2003/006359 申请日：2003-02-28
- 公开(公告)号：WO2003074671A3 公开(公告)日：2003-09-12
- 发明人： COSTA, Michael, A. , GENDREAU, Steven, Brian , DORA, Emery, G., III , NICOLL, Monique , HEUER, Timothy, S.
- 申请人： EXELIXIS, INC. , COSTA, Michael, A. , GENDREAU, Steven, Brian , DORA, Emery, G., III , NICOLL, Monique , HEUER, Timothy, S.
- 申请人地址： P.O. Box 511, 170 Harbor Way, South San Francisco, CA 94083-0511 US
- 专利权人： EXELIXIS, INC.,COSTA, Michael, A.,GENDREAU, Steven, Brian,DORA, Emery, G., III,NICOLL, Monique,HEUER, Timothy, S.
- 当前专利权人： EXELIXIS, INC.,COSTA, Michael, A.,GENDREAU, Steven, Brian,DORA, Emery, G., III,NICOLL, Monique,HEUER, Timothy, S.
- 当前专利权人地址： P.O. Box 511, 170 Harbor Way, South San Francisco, CA 94083-0511 US
- 代理机构： SHAYESTEH, Laleh
- 优先权： US60/361,243 20020301
- 主分类号： C12Q1/00
- IPC分类号： C12Q1/00
摘要：
Human MBCAT genes are identified as modulators of the beta-catenin pathway, and thus are therapeutic targets for disorders associated with defective beta-catenin function. Methods for identifying modulators of beta-catenin, comprising screening for agents that modulate the activity of MBCAT are provided.