发明申请
WO2003066001A3 ZINC SALT COMPOSITIONS FOR THE PREVENTION OF MUCOSAL IRRITATION FROM SPERMICIDES AND MICROBICIDES
审中-公开
基本信息:
- 专利标题： ZINC SALT COMPOSITIONS FOR THE PREVENTION OF MUCOSAL IRRITATION FROM SPERMICIDES AND MICROBICIDES
- 申请号：PCT/US2003/003896 申请日：2003-02-07
- 公开(公告)号：WO2003066001A3 公开(公告)日：2003-08-14
- 发明人： MODAK, Shanta, M. , GAONKAR, Trupti , CARAOS, Lauser
- 申请人： THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK , MODAK, Shanta, M. , GAONKAR, Trupti , CARAOS, Lauser
- 申请人地址： 116th Street and Broadway, New York, NY 10027 US
- 专利权人： THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK,MODAK, Shanta, M.,GAONKAR, Trupti,CARAOS, Lauser
- 当前专利权人： THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK,MODAK, Shanta, M.,GAONKAR, Trupti,CARAOS, Lauser
- 当前专利权人地址： 116th Street and Broadway, New York, NY 10027 US
- 代理机构： KOLE, Lisa, B.
- 优先权： US60/355,549 20020207
- 主分类号： A01N37/36
- IPC分类号： A01N37/36
摘要：
The addition of low concentrations of combinations of water-soluble organic salts of zinc to gels, creams, lotions or ointments can increase the ability of these products to reduce or prevent exogenous irritants from causing irritation of the underlying substrate. The addition of low concentrations of combinations of water-soluble organic zinc salts to these gels, creams, lotions or ointments also can reduce the irritation of skin or mucous membranes caused by the addition of potentially-irritating substances such as spermicides, microbicides, fungicides or other therapeutic agents to the gel, cream, lotion or ointment. The advantages of this anti-irritant approach over others, which generally employ high concentrations of single zinc salts, are the reduced potential for zinc toxicity, the reduced potential for toxicity related to zinc itself, and the preservation of the desirable biological properties of potentially-irritating therapeutic substances added to the gel, cream, lotion or ointment.