基本信息:
- 专利标题： PHOSPHORUS-CONTAINING COMPOUNDS & USES THEREOF
- 申请号：PCT/US2003/003030 申请日：2003-02-03
- 公开(公告)号：WO2003064383A3 公开(公告)日：2003-08-07
- 发明人： BERSTEIN, David, L. , METCALF, Chester, A., III , ROZAMUS, Leonard, W. , WANG, Yihan
- 申请人： ARIAD GENE THERAPEUTICS, INC. , BERSTEIN, David, L. , METCALF, Chester, A., III , ROZAMUS, Leonard, W. , WANG, Yihan
- 申请人地址： 26 Landsdowne Street, Cambridge, MA 02139 US
- 专利权人： ARIAD GENE THERAPEUTICS, INC.,BERSTEIN, David, L.,METCALF, Chester, A., III,ROZAMUS, Leonard, W.,WANG, Yihan
- 当前专利权人： ARIAD GENE THERAPEUTICS, INC.,BERSTEIN, David, L.,METCALF, Chester, A., III,ROZAMUS, Leonard, W.,WANG, Yihan
- 当前专利权人地址： 26 Landsdowne Street, Cambridge, MA 02139 US
- 代理机构： BERSTEIN, David, L.
- 优先权： US60/353,252 20020201; US60/426,928 20021115; US60/428,383 20021122; US60/433,930 20021217
- 主分类号： C07D491/06
- IPC分类号： C07D491/06
摘要：
This invention concerns a new family of phosphorus-containing compounds containing a moiety JQA- in which: A is absent or is -O-, -S- or -NR 2 -; Q is absent or (if A is -O-, -S- or -NR 2 -) Q may be -V-, -OV-, -SV-, or -NR 2 V-, where V is an aliphatic, heteroaliphatic, aryl, or heteroaryl moiety, such that J is linked to the cyclohexyl ring directly, through A or through VA, OVA, SVA or NR 2 VA; J = (I) - or - (II), K is O or S; each occurrence of Y is independently -O-, -S-, -NR 2 -, or chemical bond linking a R 5 moiety to P; and the other variables are as defined herein.