基本信息:
- 专利标题： MOLECULES FOR DIAGNOSTICS AND THERAPEUTICS
- 专利标题（中）：分子诊断和治疗
- 申请号：PCT/US2003/001096 申请日：2003-01-13
- 公开(公告)号：WO2003062376A2 公开(公告)日：2003-07-31
- 发明人： JONES, Anissa, L. , DAHL, Christopher, R. , GIETZEN, Darryl , CHINN, Joyce , DUFOUR, Gerard, E. , JACKSON, Jennifer, L. , YU, Jimmy, Y. , TUASON, Olivia , YAP, Pierre, E. , AMSHEY, Stefan, R. , DAM, Tam, C. , LIU, Tommy, F. , GERSTIN, JR., Edward, H. , PERALTA, Careyna, H. , LEWIS, Samantha, A. , CHEN, Alice , MARWAHA, Rakesh , LAN, Ruth, Y. , URASHKA, Michael, E. , KRISTNAM, Sreenivasa, R. , KOLLURU, Vijaykumar , PANESAR, Iqbal, S.
- 申请人： INCYTE GENOMICS, INC. , JONES, Anissa, L. , DAHL, Christopher, R. , GIETZEN, Darryl , CHINN, Joyce , DUFOUR, Gerard, E. , JACKSON, Jennifer, L. , YU, Jimmy, Y. , TUASON, Olivia , YAP, Pierre, E. , AMSHEY, Stefan, R. , DAM, Tam, C. , LIU, Tommy, F. , GERSTIN, JR., Edward, H. , PERALTA, Careyna, H. , LEWIS, Samantha, A. , CHEN, Alice , MARWAHA, Rakesh , LAN, Ruth, Y. , URASHKA, Michael, E. , KRISTNAM, Sreenivasa, R. , KOLLURU, Vijaykumar , PANESAR, Iqbal, S.
- 申请人地址： 3160 Porter Drive, Palo Alto, CA 94304 US
- 专利权人： INCYTE GENOMICS, INC.,JONES, Anissa, L.,DAHL, Christopher, R.,GIETZEN, Darryl,CHINN, Joyce,DUFOUR, Gerard, E.,JACKSON, Jennifer, L.,YU, Jimmy, Y.,TUASON, Olivia,YAP, Pierre, E.,AMSHEY, Stefan, R.,DAM, Tam, C.,LIU, Tommy, F.,GERSTIN, JR., Edward, H.,PERALTA, Careyna, H.,LEWIS, Samantha, A.,CHEN, Alice,MARWAHA, Rakesh,LAN, Ruth, Y.,URASHKA, Michael, E.,KRISTNAM, Sreenivasa, R.,KOLLURU, Vijaykumar,PANESAR, Iqbal, S.
- 当前专利权人： INCYTE GENOMICS, INC.,JONES, Anissa, L.,DAHL, Christopher, R.,GIETZEN, Darryl,CHINN, Joyce,DUFOUR, Gerard, E.,JACKSON, Jennifer, L.,YU, Jimmy, Y.,TUASON, Olivia,YAP, Pierre, E.,AMSHEY, Stefan, R.,DAM, Tam, C.,LIU, Tommy, F.,GERSTIN, JR., Edward, H.,PERALTA, Careyna, H.,LEWIS, Samantha, A.,CHEN, Alice,MARWAHA, Rakesh,LAN, Ruth, Y.,URASHKA, Michael, E.,KRISTNAM, Sreenivasa, R.,KOLLURU, Vijaykumar,PANESAR, Iqbal, S.
- 当前专利权人地址： 3160 Porter Drive, Palo Alto, CA 94304 US
- 代理机构： HAMLET-COX, Diana
- 优先权： US60/349,384 20020116; US60/349,946 20020117; US60/349,413 20020117
- 主分类号： C12N
- IPC分类号： C12N
摘要：
The present invention provides purified human polynucleotides for diagnostics and therapeutics (dithp). Also encompassed are the polypeptides (DITHP) encoded by dithp. The invention also provides for the use of dithp, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing dithp for the expression of DITHP. The invention additionally provides for the use of isolated and purified DITHP to induce antibodies and to screen libraries of compounds and the use of anti-DITHP antibodies in diagnostic assays. Also provided are microarrays containing dithp and methods of use.
摘要（中）：
本发明提供了用于诊断和治疗的纯化的人多核苷酸（dithp）。 还包括由dithp编码的多肽（DITHP）。 本发明还提供了在诊断测定中使用寡核苷酸，寡核苷酸或其片段。 本发明进一步提供了用于表达DITHP的含有dithp的载体和宿主细胞。 本发明另外提供了使用分离和纯化的DITHP诱导抗体并筛选化合物文库和抗DITHP抗体在诊断测定中的用途。 还提供含有dithp和使用方法的微阵列。
公开/授权文献:
- WO2003062376A3 MOLECULES FOR DIAGNOSTICS AND THERAPEUTICS 公开/授权日：2003-07-31