基本信息:
- 专利标题： HYBRID BIOLOGIC/SYNTHETIC POROUS EXTRACELLULAR MATRIX SCAFFOLDS
- 专利标题（中）：混合生物学/合成多孔细胞基质谱
- 申请号：PCT/US2002/022409 申请日：2002-07-15
- 公开(公告)号：WO2003007790A2 公开(公告)日：2003-01-30
- 发明人： MALAVIYA, Prasanna , MELICAN, Mora, C. , REZANIA, Alireza , CHUN, Iksoo
- 申请人： DEPUY PRODUCTS, INC. , MALAVIYA, Prasanna , MELICAN, Mora, C. , REZANIA, Alireza , CHUN, Iksoo
- 申请人地址： 700 Orthopaedic Drive, Warsaw, IN 46581 US
- 专利权人： DEPUY PRODUCTS, INC.,MALAVIYA, Prasanna,MELICAN, Mora, C.,REZANIA, Alireza,CHUN, Iksoo
- 当前专利权人： DEPUY PRODUCTS, INC.,MALAVIYA, Prasanna,MELICAN, Mora, C.,REZANIA, Alireza,CHUN, Iksoo
- 当前专利权人地址： 700 Orthopaedic Drive, Warsaw, IN 46581 US
- 代理机构： COFFEY, William, R.
- 优先权： US60/305,786 20010716; US60/388,711 20020614
- 主分类号： A61B
- IPC分类号： A61B
摘要：
Methods of making a hybrid biologic/synthetic scaffold for repairing damaged or diseased tissue are provided. The methods include the step of suspending pieces of an extracellular matrix material in a liquid to form a slurry, and coating a synthetic mat with the slurry, or mixing or layering the slurry with a synthetic polymer solution. The liquid is subsequently driven off so as to form a foam. Porous implantable scaffolds fabricated by such a method are also disclosed.
摘要（中）：
提供了用于修复损伤或患病组织的混合生物/合成支架的方法。 所述方法包括将细胞外基质材料块悬浮在液体中以形成浆料，并用浆料涂覆合成垫，或者用合成聚合物溶液混合或分层浆料的步骤。 随后将液体排出以形成泡沫。 还公开了通过这种方法制造的多孔可植入支架。