基本信息:
- 专利标题： THERAPEUTIC POLYPEPTIDES, NUCLEIC ACIDS ENCODING SAME, AND METHODS OF USE
- 专利标题（中）：治疗性多肽，编码其的核酸及其使用方法
- 申请号：PCT/US2002/014341 申请日：2002-05-02
- 公开(公告)号：WO2002090568A2 公开(公告)日：2002-11-14
- 发明人： ALSOBROOK, John, P., II , ANDERSON, David, W. , BOLDOG, Ferenc, L. , BURGESS, Catherine, E. , CASMAN, Stacie, J. , EDINGER, Schlomit, R. , ELLERMAN, Karen , GANGOLLI, Esha, A. , GERLACH, Valerie, L. , GORMAN, Linda , GUNTHER, Erik , HERRMANN, John, L. , JI, Weizhen , LEPLEY, Denise, M. , LEWIN, David, A. , LI, Li , MACDOUGALL, John, R. , MALYANKAR, Uriel, M. , MEZES, Peter, D. , PADIGARU, Muralidhara , PATTURAJAN, Meera , PEYMAN, John, A. , RASTELLI, Luca , RIEGER, Daniel, K. , ROTHENBERG, Mark, E. , SHENOY, Suresh, G. , SMITHSON, Glennda , SPYTEK, Kimberly, A. , STONE, David, J. , TAUPIER, Raymond, J., Jr. , TCHERNEV, Velizar, T. , VERNET, Corine, A., M. , VOSS, Edward, Z. , ZERHUSEN, Bryan, D. , ZHONG, Haihong , MILLER, Charles, E.
- 申请人： CURAGEN CORPORATION , ALSOBROOK, John, P., II , ANDERSON, David, W. , BOLDOG, Ferenc, L. , BURGESS, Catherine, E. , CASMAN, Stacie, J. , EDINGER, Schlomit, R. , ELLERMAN, Karen , GANGOLLI, Esha, A. , GERLACH, Valerie, L. , GORMAN, Linda , GUNTHER, Erik , HERRMANN, John, L. , JI, Weizhen , LEPLEY, Denise, M. , LEWIN, David, A. , LI, Li , MACDOUGALL, John, R. , MALYANKAR, Uriel, M. , MEZES, Peter, D. , PADIGARU, Muralidhara , PATTURAJAN, Meera , PEYMAN, John, A. , RASTELLI, Luca , RIEGER, Daniel, K. , ROTHENBERG, Mark, E. , SHENOY, Suresh, G. , SMITHSON, Glennda , SPYTEK, Kimberly, A. , STONE, David, J. , TAUPIER, Raymond, J., Jr. , TCHERNEV, Velizar, T. , VERNET, Corine, A., M. , VOSS, Edward, Z. , ZERHUSEN, Bryan, D. , ZHONG, Haihong , MILLER, Charles, E.
- 申请人地址： 555 Long Wharf Drive, 11th floor, New Haven, CT 06511 US
- 专利权人： CURAGEN CORPORATION,ALSOBROOK, John, P., II,ANDERSON, David, W.,BOLDOG, Ferenc, L.,BURGESS, Catherine, E.,CASMAN, Stacie, J.,EDINGER, Schlomit, R.,ELLERMAN, Karen,GANGOLLI, Esha, A.,GERLACH, Valerie, L.,GORMAN, Linda,GUNTHER, Erik,HERRMANN, John, L.,JI, Weizhen,LEPLEY, Denise, M.,LEWIN, David, A.,LI, Li,MACDOUGALL, John, R.,MALYANKAR, Uriel, M.,MEZES, Peter, D.,PADIGARU, Muralidhara,PATTURAJAN, Meera,PEYMAN, John, A.,RASTELLI, Luca,RIEGER, Daniel, K.,ROTHENBERG, Mark, E.,SHENOY, Suresh, G.,SMITHSON, Glennda,SPYTEK, Kimberly, A.,STONE, David, J.,TAUPIER, Raymond, J., Jr.,TCHERNEV, Velizar, T.,VERNET, Corine, A., M.,VOSS, Edward, Z.,ZERHUSEN, Bryan, D.,ZHONG, Haihong,MILLER, Charles, E.
- 当前专利权人： CURAGEN CORPORATION,ALSOBROOK, John, P., II,ANDERSON, David, W.,BOLDOG, Ferenc, L.,BURGESS, Catherine, E.,CASMAN, Stacie, J.,EDINGER, Schlomit, R.,ELLERMAN, Karen,GANGOLLI, Esha, A.,GERLACH, Valerie, L.,GORMAN, Linda,GUNTHER, Erik,HERRMANN, John, L.,JI, Weizhen,LEPLEY, Denise, M.,LEWIN, David, A.,LI, Li,MACDOUGALL, John, R.,MALYANKAR, Uriel, M.,MEZES, Peter, D.,PADIGARU, Muralidhara,PATTURAJAN, Meera,PEYMAN, John, A.,RASTELLI, Luca,RIEGER, Daniel, K.,ROTHENBERG, Mark, E.,SHENOY, Suresh, G.,SMITHSON, Glennda,SPYTEK, Kimberly, A.,STONE, David, J.,TAUPIER, Raymond, J., Jr.,TCHERNEV, Velizar, T.,VERNET, Corine, A., M.,VOSS, Edward, Z.,ZERHUSEN, Bryan, D.,ZHONG, Haihong,MILLER, Charles, E.
- 当前专利权人地址： 555 Long Wharf Drive, 11th floor, New Haven, CT 06511 US
- 代理机构： ELRIFI, Ivor, R.
- 优先权： US60/288,935 20010503; US60/289,087 20010507; US60/289,620 20010508; US60/289,621 20010508; US60/289,817 20010509; US60/289,818 20010509; US60/290,194 200105011; US60/290,753 200105014; US60/291,189 200105015; US60/291,243 200105016; US60/292,001 200105018; US60/292,374 200105021; US60/292,587 200105022; US60/293,107 200105023; US60/293,589 200105024; US60/293,747 200105025; US60/294,110 200105029; US60/294,434 200105030; US60/312,192 200108014; US60/313,173 200108017; US60/313,187 200108017; US60/318,728 200109012; US60/318,744 200109012; US60/335,910 2001011015; US60/333,942 2001011028; US60/333,891 2001011028; US60/345,776 20020103; US60/345,220 20020104; US10/136,071 20020501
- 主分类号： C12Q
- IPC分类号： C12Q
摘要：
Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the-polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
摘要（中）：
本文公开了编码G偶联的蛋白质 - 受体相关多肽的核酸序列。 还公开了由这些核酸序列编码的多肽，以及免疫特异性结合多肽的抗体以及上述多肽，多核苷酸或抗体的衍生物，变体，突变体或片段。 本发明还公开了用于诊断，治疗和预防与这些新型人核酸和蛋白质中的任一种相关的病症的治疗，诊断和研究方法。