Compounds useful in the treatment of inflammation structurally represented as formula (I) or pharmaceutically acceptable salts thereof, wherein R is a) (CH2)n-Y i) where n is 1 then Y is C1-C6 alkoxy, morpholinyl, piperdinyl, pyrrolidinyl, phenoxy, phenylthio, phenylsulfonyl, phenylsulfinyl, -NHC(O)-C1-C6 carboxylic acid, N3, NH2, diethylamino, hydrogen (provided R is benzyloxy), halogen (provided R is a C1-C6 alkyl) or CH("EWG")2 where "EWG" is an electron withdrawing group each individually selected from the group consisting of CO2R or PO(OR )2, or ii) n is 2 then Y is CH("EWG")2, or b) a terminal olefin substituted with i) an aryl or heteroaryl, ii) hydroxyl and a C1-C6 alkyl, phenyl or (CH2)m-CO2R where m is 1 to 3, or c) C3-C6 cycloalkyl (optionally substituted with a halogen, (PO(OC2H5)2)2 or CN); R is hydrogen or C1-C6 alkyl; R is hydrogen, hydroxyl, C1-C6 alkyl, alkoxy, benzyloxy or phenoxy; R is hydrogen, halogen, C1-C6 alkyl, C1-C6 alkoxy, phenoxy, C1-C6 alkylthio, thiophenyl, NH2, aryl (except that R is other than phenyl when R and Y are both hydrogen) or heteroaryl; R is H, C1-C6 alkyl, benzyl, phenyl, phenyl substituted with one to five F, C1, Br, I, NO2, OCH3 or C1-C4 alkyl; and R is H, C1-C6 alkyl, benzyl, phenyl, phenyl substituted with one to five F, C1, Br, I, NO2, OCH3 or C1-C4 alkyl, or where both R 's are taken together to form a CH2-CH2, CH2-CH2-CH2 or CH2-C(CH3)2-CH2 whereby a heterocyclic ring containing the bonded P atom and the two O atoms is formed. The compounds are useful as anti-inflammatory and antiarthritic agents.