基本信息:
- 专利标题： CCK AND/OR GASTRIN RECEPTOR LIGANDS
- 专利标题（中）：CCK和/或GASTRIN受体配体
- 申请号：PCT/GB9300614 申请日：1993-03-25
- 公开(公告)号：WO9320099A3 公开(公告)日：1993-11-25
- 发明人： RYDER HAMISH , KENDRICK DAVID ALAN , SEMPLE GRAEME , MIYATA KEIJI , BATT ANDRZEJ ROMAN , MATHEWS ELIZABETH ALICE , ROOKER DAVID PHILIP , NISHIDA AKITO
- 申请人： FERRING BV , YAMANOUCHI PHARMA CO LTD , RYDER HAMISH , KENDRICK DAVID ALAN , SEMPLE GRAEME , MIYATA KEIJI , BATT ANDRZEJ ROMAN , MATHEWS ELIZABETH ALICE , ROOKER DAVID PHILIP , NISHIDA AKITO
- 专利权人： FERRING BV,YAMANOUCHI PHARMA CO LTD,RYDER HAMISH,KENDRICK DAVID ALAN,SEMPLE GRAEME,MIYATA KEIJI,BATT ANDRZEJ ROMAN,MATHEWS ELIZABETH ALICE,ROOKER DAVID PHILIP,NISHIDA AKITO
- 当前专利权人： FERRING BV,YAMANOUCHI PHARMA CO LTD,RYDER HAMISH,KENDRICK DAVID ALAN,SEMPLE GRAEME,MIYATA KEIJI,BATT ANDRZEJ ROMAN,MATHEWS ELIZABETH ALICE,ROOKER DAVID PHILIP,NISHIDA AKITO
- 优先权： GB9206757 1992-03-27
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07D207/08 ; C07D209/18 ; C07D217/14 ; C07D401/12 ; C07K5/02 ; C07K5/06 ; C07K5/078 ; C07K5/097 ; C07K5/117 ; A61K37/43 ; C07D217/12 ; C07D403/12 ; C07K5/08
摘要：
This invention relates to novel compounds with the general structure A-B-C and their pharmaceutically acceptable salts, to medicinal compositions containing them, and to the use of such medicinal compositions in the treatment of certain disease states. The compounds of the invention are represented schematically as A-B-C wherein S1-S4 are in general lypophilic residues, S5 is a polar or hydrophilic residue, and L1-L5 are optional linking units. The compounds of this invention bind to CCK and/or gastrin receptors with high affinity and are therefore useful in the treatment of diseases which involve the dysfunction of a physiological process regulated by either of these hormones.
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K38/00 | 含肽的医药配制品 |