基本信息:
- 专利标题： Sulphamyl-benzoic acid derivatives
- 专利标题（中）：磺酰苯甲酸衍生物
- 申请号：US88740969 申请日：1969-12-22
- 公开(公告)号：US3806534A 公开(公告)日：1974-04-23
- 发明人： FEIT P
- 申请人： LEO PHARM PROD LTD
- 专利权人： Leo Pharm Prod Ltd
- 当前专利权人： Leo Pharm Prod Ltd
- 优先权： GB3089869 1969-06-18; GB3803869 1969-07-29; GB6133968 1968-12-24
- 主分类号： A01D33/04
- IPC分类号： A01D33/04 ; A61K31/195 ; C07C311/37 ; C07D213/75 ; C07D295/12 ; C07C121/52
摘要：
THIS INVENTION RELATES TO NEW, THERAPEUTICALLY ACTIVE COMPOUNDS OF THE GENERAL FORMULA
1-(R4-N(-R5)-),2-A,3-(R3-N(-R6)-SO2-),5-(HOOC-)BENZENE
IN WHICH A REPRESENTS ONE OF THEGROUPINGS
R1-N(-R2)-, R2-O-,
R2-S-, R2-OS, AND R2-O2S-, R1, R2, R3, AND R4 EACH REPRESENTS HYDROGEN, AN ALIPHATIC RADICAL, A CYCLOALIPHATIC RADICAL, OR AN AROMATICALLY, CYCLOALIPHATICALLY, OR HETEROCYCLICALLY SUBSTITUTED ALIPHATIC RADICAL, IN ADDITION TO WHICH R2 AND R3 MAY EACH REPRESENT AN AROMATIC OR HETEROCYCLIC RADICAL, AND WHEN A IS R1-N(-R2)-, R1 AND R2 MAY IRON PENTACARBONYL TOGETHER WITH THE DIENE IN A SOLVENT AT TEMPERATURES WITHIN THE RANGE TROGEN ATOMS, SULPHUR ATOMS, OR OXYGEN ATOMS IN ADDITION TO THE NITROGEN ATOM LINKED TO R1 AND R2; R5 IS HYDROGEN OR LOWER ALKYL; AND R6 IS HYDROGEN OR LOWER ALKYL OR ACYL; TO SALTS, ESTERS, AND AMIDES OF THE SAID COMPOUNDS; AND TO METHODS FOR THE PRODUCTION OF THE COMPOUNDS.
1-(R4-N(-R5)-),2-A,3-(R3-N(-R6)-SO2-),5-(HOOC-)BENZENE
IN WHICH A REPRESENTS ONE OF THEGROUPINGS
R1-N(-R2)-, R2-O-,
R2-S-, R2-OS, AND R2-O2S-, R1, R2, R3, AND R4 EACH REPRESENTS HYDROGEN, AN ALIPHATIC RADICAL, A CYCLOALIPHATIC RADICAL, OR AN AROMATICALLY, CYCLOALIPHATICALLY, OR HETEROCYCLICALLY SUBSTITUTED ALIPHATIC RADICAL, IN ADDITION TO WHICH R2 AND R3 MAY EACH REPRESENT AN AROMATIC OR HETEROCYCLIC RADICAL, AND WHEN A IS R1-N(-R2)-, R1 AND R2 MAY IRON PENTACARBONYL TOGETHER WITH THE DIENE IN A SOLVENT AT TEMPERATURES WITHIN THE RANGE TROGEN ATOMS, SULPHUR ATOMS, OR OXYGEN ATOMS IN ADDITION TO THE NITROGEN ATOM LINKED TO R1 AND R2; R5 IS HYDROGEN OR LOWER ALKYL; AND R6 IS HYDROGEN OR LOWER ALKYL OR ACYL; TO SALTS, ESTERS, AND AMIDES OF THE SAID COMPOUNDS; AND TO METHODS FOR THE PRODUCTION OF THE COMPOUNDS.