发明申请
US20230098944A1 METHOD OF DECREASING AMYLOID BETA MONOMER LEVELS IN PATIENTS WITH COGNITIVE DECLINE
有权
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基本信息:
- 专利标题: METHOD OF DECREASING AMYLOID BETA MONOMER LEVELS IN PATIENTS WITH COGNITIVE DECLINE
- 申请号:US17798667 申请日:2021-02-12
- 公开(公告)号:US20230098944A1 公开(公告)日:2023-03-30
- 发明人: Susan CATALANO , Nicholas IZZO
- 申请人: Cognition Therapeutics, Inc.
- 申请人地址: US PA Pittsburgh
- 专利权人: Cognition Therapeutics, Inc.
- 当前专利权人: Cognition Therapeutics, Inc.
- 当前专利权人地址: US PA Pittsburgh
- 国际申请: PCT/US2021/018023 WO 20210212
- 主分类号: A61K31/4035
- IPC分类号: A61K31/4035 ; A61P25/28
摘要:
The present disclosure relates to methods of decreasing amyloid β monomers and methods of treating cognitive decline in a subject, wherein the treatment results in an increase in amyloid β oligomers and a reduction in cognitive decline. The present disclosure relates to treating cognitive decline, wherein target engagement can be measured in the clinic after treating.
IPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |
------A61K31/00 | 含有机有效成分的医药配制品 |
--------A61K31/33 | .杂环化合物 |
----------A61K31/335 | ..仅有氧作为环杂原子的,例如制霉色基素 |
------------A61K31/40 | ...有仅以1个氮作为环杂原子的五元环的,例如舒必利、琥珀酰亚胺、托尔米丁、甲氧吡丁苯 |
--------------A61K31/403 | ....与碳环稠合的,例如咔唑 |
----------------A61K31/4035 | .....异吲哚类,例如肽酰亚胺 |