基本信息:
- 专利标题： METHOD FOR IMPROVING PRODUCTION OF STREPTOMYCES POLYKETIDE COMPOUNDS
- 申请号：US17611992 申请日：2020-05-15
- 公开(公告)号：US20230056311A1 公开(公告)日：2023-02-23
- 发明人： Lixin ZHANG , Weishan WANG , Shanshan LI , Zilong LI , Gaoyi TAN , Jingyu ZHANG
- 申请人： EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY , INSTITUTE OF MICROBIOLOGY, CHINESE ACADEMY OF SCIENCES
- 申请人地址： CN Shanghai; CN Beijing
- 专利权人： EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY,INSTITUTE OF MICROBIOLOGY, CHINESE ACADEMY OF SCIENCES
- 当前专利权人： EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY,INSTITUTE OF MICROBIOLOGY, CHINESE ACADEMY OF SCIENCES
- 当前专利权人地址： CN Shanghai; CN Beijing
- 优先权： CN201910411123.7 20190517
- 国际申请： PCT/CN2020/090452 WO 20200515
- 主分类号： C12P13/00
- IPC分类号： C12P13/00 ; C12N15/01 ; C12N1/20 ; C12N9/02 ; C12N9/10 ; C12N9/16 ; C12P17/16 ; C12P17/18
摘要：
A method for improving the production of Streptomyces polyketide compounds is provided. The method greatly improves the capability of the Streptomyces polyketide compounds by strengthening a triacylglycerol decomposition pathway in Streptomyces during the stationary phase. A method for switching the primary metabolism of Streptomyces to the secondary metabolism, Streptomyces producing polyketide compounds, and use thereof are also provided.
IPC结构图谱:
| C | 化学；冶金 |
| --C12 | 生物化学；啤酒；烈性酒；果汁酒；醋；微生物学；酶学；突变或遗传工程 |
| ----C12P | 发酵或使用酶的方法合成目标化合物或组合物或从外消旋混合物中分离旋光异构体 |
| ------C12P13/00 | 含氮有机化合物的制备 |