基本信息:
- 专利标题： THERAPEUTIC ANTICANCER NEOEPITOPE VACCINE
- 申请号：US17557988 申请日：2021-12-21
- 公开(公告)号：US20220370579A1 公开(公告)日：2022-11-24
- 发明人： Stine Granum , Elisabeth Stubsrud , Agnete Brunsvik Fredriksen
- 申请人： NYKODE THERAPEUTICS ASA
- 申请人地址： NO Oslo
- 专利权人： NYKODE THERAPEUTICS ASA
- 当前专利权人： NYKODE THERAPEUTICS ASA
- 当前专利权人地址： NO Oslo
- 优先权： EP16150574.8 20160108,EP16178393.1 20160707
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61P35/00
摘要：
The present invention relates to an anticancer vaccine which includes polynucleotides or polypeptides, methods of treatment of cancer wherein such an anticancer vaccine is used as well as methods for producing the vaccine. The vaccine includes a polynucleotide with a nucleotide sequence encoding a targeting unit, a dimerization unit, a first linker and an antigenic unit. The antigenic unit includes from 3 to 50 antigenic subunits separated by a second linker with each antigenic subunit having at least a part of a cancer neoepitope sequence. The vaccine can include a polypeptide encoded by the polynucleotide or a dimeric protein with two polypeptides encoded by the polynucleotide.
公开/授权文献:
- US12059459B2 Therapeutic anticancer neoepitope vaccine 公开/授权日：2024-08-13
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K39/00 | 含有抗原或抗体的医药配制品 |