基本信息:
- 专利标题： DRUG DELIVERY FROM HYDROGELS
- 申请号：US17830968 申请日：2022-06-02
- 公开(公告)号：US20220370419A1 公开(公告)日：2022-11-24
- 发明人： Peter Jarrett , Rami El-Hayek , Timothy S. Jarrett , Charles D. Blizzard , Amarpreet S. Sawhney
- 申请人： Incept, LLC
- 申请人地址： US MA Lexington
- 专利权人： Incept, LLC
- 当前专利权人： Incept, LLC
- 当前专利权人地址： US MA Lexington
- 主分类号： A61K31/436
- IPC分类号： A61K31/436 ; A61K31/44 ; A61K31/404 ; A61K31/502 ; A61K31/496 ; A61K31/56 ; A61K31/517 ; A61K31/444 ; A61K9/00
摘要：
Drug delivery involving hydrogels as used for various medical conditions, and includes hydrogels formed in an eye with extended drug release times. An embodiment of the invention is a method of delivering a therapeutic agent to a tissue comprising forming a hydrogel in situ in an eye with a therapeutic agent dispersed in the hydrogel, the agent having a low solubility in water. The agent may be essentially insoluble in water. The hydrogel may be made so that 50% to 100% w/w of the agent is released when the hydrogel is from 100% to 50% persistent, with the persistence being a measure of the dry weight of the hydrogel relative to an initial dry weight of the hydrogel.
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K31/00 | 含有机有效成分的医药配制品 |
| --------A61K31/33 | .杂环化合物 |
| ----------A61K31/335 | ..仅有氧作为环杂原子的，例如制霉色基素 |
| ------------A61K31/40 | ...有仅以1个氮作为环杂原子的五元环的，例如舒必利、琥珀酰亚胺、托尔米丁、甲氧吡丁苯 |
| --------------A61K31/4353 | ....与杂环邻位稠合或迫位稠合的 |
| ----------------A61K31/436 | .....含有氧作为环杂原子的六元环的杂环系统，例如雷帕霉素 |