发明申请
US20220033460A1 IDENTIFICATION AND USE OF T CELL EPITOPES IN DESIGNING DIAGNOSTIC AND THERAPEUTIC APPROACHES FOR COVID-19
有权
基本信息:
- 专利标题： IDENTIFICATION AND USE OF T CELL EPITOPES IN DESIGNING DIAGNOSTIC AND THERAPEUTIC APPROACHES FOR COVID-19
- 申请号：US17397841 申请日：2021-08-09
- 公开(公告)号：US20220033460A1 公开(公告)日：2022-02-03
- 发明人： Daniel Pregibon , Joshua Francis , Del Leistritz-Edwards , William Dunn , Violeta Rayon Estrada , Gang Liu , Jan Kisielow , Franz-Josef Obermair
- 申请人： Repertoire Immune Medicines, Inc. , Repertoire Immune Medicines (Switzerland) Ltd.
- 申请人地址： US MA Cambridge; CH Schlieren
- 专利权人： Repertoire Immune Medicines, Inc.,Repertoire Immune Medicines (Switzerland) Ltd.
- 当前专利权人： Repertoire Immune Medicines, Inc.,Repertoire Immune Medicines (Switzerland) Ltd.
- 当前专利权人地址： US MA Cambridge; CH Schlieren
- 主分类号： C07K14/725
- IPC分类号： C07K14/725 ; A61K39/215 ; C12N5/0783 ; C07K14/74 ; A61K35/17
摘要：
Approaches for identifying T cell epitopes from SARS-CoV-2 are provided, along with the use of such T cell epitopes diagnostically and therapeutically. Compositions including T cell epitope vaccines and T cell epitope-display reagents are provided. Methods for identifying SARS-CoV-2 T cell epitopes, methods of identifying reactive T cells and methods of using epitopes and T cells for diagnostic purposes, such as identifying particular patient subpopulations are provided. Treatment methods, including administration of T cell epitope vaccines prophylactically and administration of activated T cells therapeutically are also provided.
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07K | 肽 |
| ------C07K14/00 | 具有多于20个氨基酸的肽；促胃液素；生长激素释放抑制因子；促黑激素；其衍生物 |
| --------C07K14/415 | .来自植物 |
| ----------C07K14/44 | ..来自原生动物门 |
| ------------C07K14/725 | ...T-细胞受体 |