发明申请
US20210239617A1 DEVICE AND METHOD FOR DETERMINING DEPTH AND CONCENTRATION OF A SUBSURFACE FLUORESCENT OBJECT
有权
基本信息:
- 专利标题： DEVICE AND METHOD FOR DETERMINING DEPTH AND CONCENTRATION OF A SUBSURFACE FLUORESCENT OBJECT
- 申请号：US17050745 申请日：2019-04-26
- 公开(公告)号：US20210239617A1 公开(公告)日：2021-08-05
- 发明人： Keith D. Paulsen , David W. Roberts , Dennis Wirth , Brian C. Wilson , Mira Sibai
- 申请人： THE TRUSTEES OF DARTMOUTH COLLEGE , UNIVERSITY HEALTH NETWORK
- 申请人地址： US NH Hanover; CA Toronto
- 专利权人： THE TRUSTEES OF DARTMOUTH COLLEGE,UNIVERSITY HEALTH NETWORK
- 当前专利权人： THE TRUSTEES OF DARTMOUTH COLLEGE,UNIVERSITY HEALTH NETWORK
- 当前专利权人地址： US NH Hanover; CA Toronto
- 国际申请： PCT/US19/29421 WO 20190426
- 主分类号： G01N21/64
- IPC分类号： G01N21/64 ; G01N33/483 ; G01B11/22 ; G01N21/47
摘要：
A method and device for determining the depth and fluorophore concentration of a fluorophore concentration below the surface of an optically absorbing and scattering medium suitable for use in fluorescence-based surgical guidance such as in tumor resection is described. Long-wavelength stimulus light us used to obtain deep tissue penetration. Recovery of depth is performed by fitting measured modulation amplitudes for each spatial frequency to precomputed modulation amplitudes in a table of modulation amplitudes indexed by optical parameters and depth.
公开/授权文献:
IPC结构图谱:
| G | 物理 |
| --G01 | 测量；测试 |
| ----G01N | 借助于测定材料的化学或物理性质来测试或分析材料 |
| ------G01N21/00 | 利用光学手段，即利用红外光、可见光或紫外光来测试或分析材料 |
| --------G01N21/01 | .便于进行光学测试的装置或仪器 |
| ----------G01N21/63 | ..光学激发的 |
| ------------G01N21/64 | ...荧光；磷光 |