基本信息:
- 专利标题： FUSED TRICYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE
- 申请号：US17266961 申请日：2019-08-27
- 公开(公告)号：US20210236493A1 公开(公告)日：2021-08-05
- 发明人： Jianzhou HUANG , Qingyun REN , Jinfeng XIONG , Yang LIU , Xinchang LIU , Siegfried GOLDMANN , Yingjun ZHANG , Yifeng WANG , Weishun LIU , Fangcai YU
- 申请人： SUNSHINE LAKE PHARMA CO., LTD.
- 申请人地址： CN Dongguan, Guangdong
- 专利权人： SUNSHINE LAKE PHARMA CO., LTD.
- 当前专利权人： SUNSHINE LAKE PHARMA CO., LTD.
- 当前专利权人地址： CN Dongguan, Guangdong
- 优先权： CN201810985779.5 20180828,CN201910201731.5 20190318
- 国际申请： PCT/CN2019/102754 WO 20190827
- 主分类号： A61K31/5025
- IPC分类号： A61K31/5025 ; A61K31/7068 ; A61K31/675 ; A61K38/21 ; A61K38/20 ; A61K31/7056 ; A61K31/52 ; A61K31/427 ; A61K31/7072 ; A61K31/429 ; A61P31/20 ; C07D471/04
摘要：
A fused tricyclic compound and application thereof in medicine, especially as a medicament for the treatment and/or prevention of hepatitis B. Specifically, the present invention relates to a compound having Formula (I) or a stereoisomer, a tautomer, an N-oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, wherein each variable is as defined in the specification. The present invention also relates to the use of a compound having Formula (I) or a stereoisomer, a tautomer, an N-oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof as a medicament, especially as a medicament for the treatment and/or prevention of hepatitis B.
公开/授权文献:
- US12128044B2 Fused tricyclic compounds and uses thereof in medicine 公开/授权日：2024-10-29
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K31/00 | 含有机有效成分的医药配制品 |
| --------A61K31/33 | .杂环化合物 |
| ----------A61K31/335 | ..仅有氧作为环杂原子的，例如制霉色基素 |
| ------------A61K31/40 | ...有仅以1个氮作为环杂原子的五元环的，例如舒必利、琥珀酰亚胺、托尔米丁、甲氧吡丁苯 |
| --------------A61K31/50 | ....哒嗪；氢化哒嗪 |
| ----------------A61K31/5025 | .....与杂环邻位或迫位稠合的 |