基本信息:
- 专利标题： METHOD FOR PRODUCING CHIRAL AMINES
- 申请号：US16643829 申请日：2018-08-31
- 公开(公告)号：US20210062233A1 公开(公告)日：2021-03-04
- 发明人： Yamini SATYAWALI , Dominic ORMEROD , Claudia MATASSA , Karolien VANBROEKHOVEN
- 申请人： VITO NV
- 申请人地址： BE Mol
- 专利权人： VITO NV
- 当前专利权人： VITO NV
- 当前专利权人地址： BE Mol
- 优先权： EP17188951.2 20170901
- 国际申请： PCT/EP2018/073524 WO 20180831
- 主分类号： C12P13/00
- IPC分类号： C12P13/00 ; C12N9/10
摘要：
A method for producing a chiral amine may include performing a transamination reaction of a prochiral amino acceptor and an amino donor in a first solution in the presence of a transaminase, thereby forming a chiral amine and a co-product in the first solution. The amino donor is a high molecular weight (HMW) amino donor. In some examples, the molecular weight of the HMW amino donor is at least 150 g/mol. In some examples, the amino donor is affixed on a support, the total molecular weight of the amino donor and the support being at least 150 g/mol.
公开/授权文献:
- US11180783B2 Method for producing chiral amines 公开/授权日：2021-11-23
IPC结构图谱:
| C | 化学；冶金 |
| --C12 | 生物化学；啤酒；烈性酒；果汁酒；醋；微生物学；酶学；突变或遗传工程 |
| ----C12P | 发酵或使用酶的方法合成目标化合物或组合物或从外消旋混合物中分离旋光异构体 |
| ------C12P13/00 | 含氮有机化合物的制备 |