基本信息:
- 专利标题： Biologically Active Cannabidiol Analogs
- 申请号：US16896242 申请日：2020-06-09
- 公开(公告)号：US20210030708A1 公开(公告)日：2021-02-04
- 发明人： Mahmoud A. ElSohly , Soumyajit Majumdar , Waseem Gul , Mohammad Khalid Ashfaq , Kenneth Joseph Sufka , Hannah Marie Harris
- 申请人： University of Mississippi
- 申请人地址： US MS University
- 专利权人： University of Mississippi
- 当前专利权人： University of Mississippi
- 当前专利权人地址： US MS University
- 主分类号： A61K31/24
- IPC分类号： A61K31/24 ; C07C69/40 ; C07C69/42 ; C07C229/08 ; A61K31/05 ; A61K31/223 ; A61K31/225 ; C07C233/56 ; C07C69/017 ; C07C229/24 ; C07C233/47 ; C07C237/06
摘要：
Biologically active cannabidiol analogs comprising a compound of the formula wherein one of R1 or R2 or both is/are the residue of a moiety formed by the reaction of an amino group of the amino acid ester of R1 or R2 or both with a dicarboxylic acid or a dicarboxylic acid derivative and the other R1 or R2 (in the case of the mono) is the residue of a dicarboxylic acid or dicarboxylic acid derivative or Hydrogen (H), (i.e. underivatized), and salts thereof. These CBD analogs are be useful in pain management in oncology and other clinical settings in which neuropathy is presented. Furthermore, these CBD-analogs are useful in blocking the addictive properties of opiates.
公开/授权文献:
- US11596617B2 Biologically active cannabidiol analogs 公开/授权日：2023-03-07
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K31/00 | 含有机有效成分的医药配制品 |
| --------A61K31/045 | .羟基化合物，例如醇类；其盐类，例如醇化物 |
| ----------A61K31/215 | ..羧酸酯 |
| ------------A61K31/22 | ...无环酸的酯，例如帕伐他丁 |
| --------------A61K31/24 | ....有1个氨基或硝基的 |