基本信息:
- 专利标题： DELIVERY OF BIOMOLECULES TO PBMCs TO MODIFY AN IMMUNE RESPONSE
- 申请号：US16803937 申请日：2020-02-27
- 公开(公告)号：US20200318066A1 公开(公告)日：2020-10-08
- 发明人： Armon R. SHAREI , Howard BERNSTEIN , Scott LOUGHHEAD , Matthew BOOTY , Katarina BLAGOVIC , Kelan HLAVATY , Defne YARAR , Emrah Ilker OZAY , Carolyne Kelly SMITH
- 申请人： SQZ Biotechnologies Company
- 优先权： com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@667a2a3d
- 主分类号： C12N5/078
- IPC分类号： C12N5/078 ; A61K39/39 ; A61K39/12
摘要：
The present application provides peripheral blood mononuclear cells comprising an antigen, methods of manufacturing such PBMCs, and methods of using such PBMCs, such as for modulating an immune response in an individual. In some embodiments, the PBMCs are conditioned by incubating the PBMC in the presence of an adjuvant.