基本信息:
- 专利标题： DNA VACCINES AND METHODS FOR THE PREVENTION OF TRANSPLANTATION REJECTION
- 申请号：US16676196 申请日：2019-11-06
- 公开(公告)号：US20200316180A1 公开(公告)日：2020-10-08
- 发明人： Fengchun Li , Alan P. Escher
- 申请人： Loma Linda University
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K9/00 ; A61K45/06
摘要：
Methods for preventing, delaying the onset of, or treating rejection of an allograft using a DNA vaccine, where the vaccine can comprise a polynucleotide encoding a pro-apoptotic protein, like BAX and/or a polynucleotide encoding an autoantigen or donor antigen, like secreted glutamic acid decarboxylase 55. Administering one of the DNA vaccines to a transplant recipient, as described herein, can induce a donor specific tolerogenic response.
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K39/00 | 含有抗原或抗体的医药配制品 |