Pedestrian-Vehicle safety systems for loading docks are disclosed. An example system includes a first sensor system to determine a position of a vehicle relative to a pedestrian zone adjacent a dock wall of a loading dock and a second sensor system to monitor the pedestrian zone. The second sensor system to attempt to detect a pedestrian in the pedestrian zone, the second sensor system responsive to signals from the first sensor system to enable the second sensor system to dynamically change a sensing area of the pedestrian zone to maintain a delta threshold between the vehicle and the pedestrian zone in response to the vehicle moving toward a dock wall of the loading dock.