基本信息:
- 专利标题： TETRACYCLIC BROMODOMAIN INHIBITORS
- 申请号：US16254124 申请日：2019-01-22
- 公开(公告)号：US20190389861A1 公开(公告)日：2019-12-26
- 发明人： Steven D. Fidanze , Dachun Liu , Robert A. Mantei , Keith F. McDaniel , John Pratt , George S. Sheppard , Le Wang , Andrew Bogdan , James H. Holms , Justin D. Dietrich , Jasmina Marjanovic , Lisa A. Hasvold , Yujia Dai
- 申请人： AbbVie Inc.
- 主分类号： C07D471/22
- IPC分类号： C07D471/22 ; C07D471/16
摘要：
The present invention provides for compounds of formula (I) wherein R1, R2, R6, Y1, Y2, Y3, A1, A2, A3, and A4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D471/00 | 在稠环系中含有氮原子作为仅有的杂环原子、其中至少1个环是含有1个氮原子的六元环的杂环化合物，C07D451/00至C07D463/00不包括的 |
| --------C07D471/22 | .在稠环系中含有4个或更多个杂环 |