基本信息:
- 专利标题： NOVEL MUCOSAL ADJUVANTS AND DELIVERY SYSTEMS
- 申请号：US16379535 申请日：2019-04-09
- 公开(公告)号：US20190231869A1 公开(公告)日：2019-08-01
- 发明人： Billy M. Hargis , Neil R. Pumford , Marion Morgan , Srichaitanya Shivaramaiah , Guillermo Tellez-Isaias , Amanda Wolfenden
- 申请人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS
- 申请人地址： US AR Little Rock
- 专利权人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS
- 当前专利权人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS
- 当前专利权人地址： US AR Little Rock
- 主分类号： A61K39/39
- IPC分类号： A61K39/39 ; C08L5/08 ; A61K39/02 ; A61K39/145 ; A61K39/155 ; A61K31/7004 ; A61K39/08 ; C08B37/08 ; A61K31/722 ; A61K39/12 ; A61K39/112 ; C12N7/00
摘要：
Adjuvants comprising chitosan cross-linked with an aldehyde or mannosylated chitosan are provided herein. Methods of making the adjuvants and methods of combining or linking the adjuvants with antigens are also provided. The adjuvant-antigen combinations can be used in vaccine formulations and the vaccine formulations can be used in methods to vaccinate animals against the source of the antigen or to enhance the immune response in a subject.
公开/授权文献:
- US10780162B2 Mucosal adjuvants and delivery systems 公开/授权日：2020-09-22
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K39/00 | 含有抗原或抗体的医药配制品 |
| --------A61K39/39 | .以免疫刺激添加剂，例如化学佐剂为特征的 |