基本信息:
- 专利标题： ANG2-BINDING MOLECULES
- 申请号：US16025067 申请日：2018-07-02
- 公开(公告)号：US20190135907A1 公开(公告)日：2019-05-09
- 发明人： Rene Georg Ott , Eric Borges , Andreas Gschwind , Joachim Boucneau , Marie-Ange Buyse , Erik Depla , Pascal Merchiers , Frederik Stevenaert
- 申请人： Boehringer Ingelheim International GmbH
- 优先权： EP12162615.4 20120330
- 主分类号： C07K16/22
- IPC分类号： C07K16/22 ; C07K16/30 ; A61K45/06
摘要：
Ang2-binding molecules, preferably Ang2-binding immunoglobulin single variable domains like VHHs and domain antibodies, pharmaceutical compositions containing same and their use in the treatment of diseases that are associated with Ang2-mediated effects on angiogenesis. Nucleic acids encoding Ang2-binding molecules, host cells and methods for preparing same.