发明申请
US20190135738A1 TUNABLE NITRIC OXIDE-RELEASING MACROMOLECULES HAVING MULTIPLE NITRIC OXIDE DONOR STRUCTURES
审中-公开
基本信息:
- 专利标题： TUNABLE NITRIC OXIDE-RELEASING MACROMOLECULES HAVING MULTIPLE NITRIC OXIDE DONOR STRUCTURES
- 申请号：US16239069 申请日：2019-01-03
- 公开(公告)号：US20190135738A1 公开(公告)日：2019-05-09
- 发明人： Mark Schoenfisch , Yuan Lu , Nathan Stasko , Jian Bao
- 申请人： The University of North Carolina at Chapel Hill , Novan, Inc.
- 主分类号： C07C281/20
- IPC分类号： C07C281/20 ; C07C247/10 ; A61K31/655 ; C07C291/02
摘要：
Provided here are nitric oxide-releasing compounds that include at least two different NO donor functional groups of the same class. In some embodiments, such nitric oxide-releasing compounds are macromolecules such as dendrimer and co-condensed silica. Pharmaceutical compositions, wound dressings, kits and methods of treatments are also provided herein.
公开/授权文献:
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07C | 无环或碳环化合物 |
| ------C07C281/00 | 含有包括在C07C269/00至C07C279/00组中的官能团的碳酸的衍生物，其中至少该官能团的1个氮原子进一步连接另一个不属于硝基或亚硝基的氮原子 |
| --------C07C281/20 | .官能团的两个氮原子相互双键连接，例如，偶氮甲酰胺 |